Abstract: The present invention is a system and a method for processing and adjusting the PCM digital audio signals using specific reverberation and equalization settings that have been determined to potentially improve certain physical health parameters measurements, as determined by conducting bio-signal testing. The system includes a source of audio signals, producing an analog audio signal as input; a digital to analog converter, converting the analog audio signal to digital; a digital system processor, having a computer processor and memory or circuitry for processing the input audio signal using an equalization, a reverberation and a volume setting that is measured to produce an audio output signal that has more beneficial health response on human physiological functions than an unprocessed PCM digital signal or a base measurement without any audio signal, as measured by at least one bio-sensor attached to at least one listener.