Patents Assigned to De Staat der Nederlanden, vert. door de minister van VWS Ministerie van Volksgezondheid, Welzjin en
  • PROCESS FOR DETERGENT-FREE PRODUCTION OF OUTER MEMBRANE VESICLES OF A GRAM-NEGATIVE BACTERIUM
    Publication number: 20140147469
    Abstract: The present invention relates to the fields of medical microbiology and vaccines. In particular the invention relates to a process for detergent-free preparation of outer membrane vesicles (OMV) of Gram negative bacteria for use in vaccines, to OMV obtainable by said process, and to a pharmaceutical composition comprising such OMV. The present invention further relates to the use of OMV of the present invention as a medicament in particular for use in a method for eliciting an immune response.
    Type: Application
    Filed: July 5, 2012
    Publication date: May 29, 2014
    Applicant: De Staat der Nederlanden, vert. door de minister van VWS Ministerie van Volksgezondheid, Welzjin en
    Inventors: Bas Van De Waterbeemd, Leonardus Aldolfus Van Der Pol