Abstract: The present invention relates to a process for the preparation of cyclic 4-oxoamidines. Such substances are precursors of active substances having biological action. The process according to the invention forms a further method of obtaining this class of compound.By reacting condensation products of aldehydes and aminonitriles or amino acid amides with oxidizing agents, the desired cyclic 4-oxoamidines are obtained according to the invention in good to very good yields.
Type:
Grant
Filed:
March 25, 1999
Date of Patent:
March 14, 2000
Assignee:
Degussa-Huuls
Inventors:
Karlheinz Drauz, Rolf Hoffmann, Ivan Pilgrims