Patents Assigned to Dermagen AB
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Patent number: 8227406Abstract: The invention relates to an antimicrobial peptide comprising a first set of amino acid residues having a length of from about 2 to about 36 amino acid residues or analogues thereof linked to the amino or carboxyterminal end a second set comprising from 3 to 8 hydrophobic amino acid residue or analogue thereof, wherein said peptide has an antimicrobial activity.Type: GrantFiled: May 15, 2007Date of Patent: July 24, 2012Assignee: Dermagen ABInventors: Artur Schmidtchen, Martin Malmsten
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Patent number: 8076286Abstract: The invention relates to a molecule comprising at least the amino acid sequence X1 X2 X3 X4 X5 X6 W X8 X9 X10 wherein X4,6,9 is any amino acid residue, X1 is I, L or V, X2 is not C, X3 is A, E, Q, R or Y, X5 is not R, X8 is I or L, X10 is not H and wherein said molecule have a length of from about 10 to about 100 amino acid residues or an analogue thereof. The invention also relates to compositions comprising said molecule and use of the molecule and/or composition of the invention to combat microorganisms, such as bacteria, viruses, fungi, including yeast, and parasites.Type: GrantFiled: February 12, 2007Date of Patent: December 13, 2011Assignee: Dermagen ABInventors: Artur Schmidtchen, Martin Malmsten, Björn Walse
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Publication number: 20100159006Abstract: The invention relates to an antimicrobial peptide comprising a first set of amino acid residues having a length of from about 2 to about 36 amino acid residues or analogues thereof linked to the amino or carboxyterminal end a second set comprising from 3 to 8 hydrophobic amino acid residue or analogue thereof, wherein said peptide has an antimicrobial activityType: ApplicationFiled: May 15, 2007Publication date: June 24, 2010Applicant: Dermagen ABInventors: Artur Schmidtchen, Martin Malmsten
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Publication number: 20090312265Abstract: The invention relates to a molecule comprising at least the amino acid sequence K X K X1 X2 X K G X wherein X is any amino acid residue X1, and X2 is K or R and wherein said molecule have a length of from about 10 to about 100 amino acid residues or an analogue thereof The invention also relates to compositions comprising said molecule and use of the molecule and/or composition of the invention to combat microorganisms, such as bacteria, viruses, fungi, including yeast, and parasites.Type: ApplicationFiled: February 12, 2007Publication date: December 17, 2009Applicant: Dermagen ABInventors: Artur Schmidtchen, Martin Malmsten, Björn Walse
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Publication number: 20090074864Abstract: The invention relates to an antimicrobial peptide with heparin binding activity, being derived from endogenous mammalian proteins being substantially free from antimicrobial activity selected from the group consisting of laminin isoforms, complement factor C3, histidin rich glycoprotein and kininogen and having from 10 to 36 amino acid residues, wherein the antimicrobial peptide consists of at least four amino acid residues selected from the group consisting of K, R and H. The invention also relates to pharmaceutical compositions comprising said antimicrobial peptide and use of the antimicrobial peptide and/or antimicrobial/pharmaceutical composition.Type: ApplicationFiled: October 23, 2007Publication date: March 19, 2009Applicant: Dermagen ABInventors: Artur Schmidtchen, Martin Malmsten
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Publication number: 20080069849Abstract: The invention relates to the use of peptides, wherein at least one amino acid residue has been substituted to improve the efficacy of the antimicrobial peptide for the manufacturing of an antimicrobial composition. The composition can be used as a pharmaceutical composition to combat microorganisms, such as bacteria, virus, fungus, parasites as well as yeast.Type: ApplicationFiled: November 17, 2005Publication date: March 20, 2008Applicant: Dermagen ABInventors: Artur Schmidtchen, Martin Malmsten, Bjorn Walse
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Publication number: 20070185019Abstract: The invention relates to an antimicrobial peptide with heparin binding activity, being derived from endogenous mammalian proteins being substantially free from antimicrobial activity selected from the group consisting of laminin isoforms, complement factor C3, histidin rich glycoprotein and kininogen and having from 10 to 36 amino acid residues, wherein the antimicrobial peptide consists of at least four amino acid residues selected from the group consisting of K, R and H. The invention also relates to pharmaceutical compositions comprising said antimicrobial peptide and use of the antimicrobial peptide and/or antimicrobial/pharmaceutical composition.Type: ApplicationFiled: May 19, 2004Publication date: August 9, 2007Applicant: DERMAGEN ABInventors: Artur Schmidtchen, Martin Malmsten