Patents Assigned to Dermagen AB
  • Patent number: 8227406
    Abstract: The invention relates to an antimicrobial peptide comprising a first set of amino acid residues having a length of from about 2 to about 36 amino acid residues or analogues thereof linked to the amino or carboxyterminal end a second set comprising from 3 to 8 hydrophobic amino acid residue or analogue thereof, wherein said peptide has an antimicrobial activity.
    Type: Grant
    Filed: May 15, 2007
    Date of Patent: July 24, 2012
    Assignee: Dermagen AB
    Inventors: Artur Schmidtchen, Martin Malmsten
  • Patent number: 8076286
    Abstract: The invention relates to a molecule comprising at least the amino acid sequence X1 X2 X3 X4 X5 X6 W X8 X9 X10 wherein X4,6,9 is any amino acid residue, X1 is I, L or V, X2 is not C, X3 is A, E, Q, R or Y, X5 is not R, X8 is I or L, X10 is not H and wherein said molecule have a length of from about 10 to about 100 amino acid residues or an analogue thereof. The invention also relates to compositions comprising said molecule and use of the molecule and/or composition of the invention to combat microorganisms, such as bacteria, viruses, fungi, including yeast, and parasites.
    Type: Grant
    Filed: February 12, 2007
    Date of Patent: December 13, 2011
    Assignee: Dermagen AB
    Inventors: Artur Schmidtchen, Martin Malmsten, Björn Walse
  • Publication number: 20100159006
    Abstract: The invention relates to an antimicrobial peptide comprising a first set of amino acid residues having a length of from about 2 to about 36 amino acid residues or analogues thereof linked to the amino or carboxyterminal end a second set comprising from 3 to 8 hydrophobic amino acid residue or analogue thereof, wherein said peptide has an antimicrobial activity
    Type: Application
    Filed: May 15, 2007
    Publication date: June 24, 2010
    Applicant: Dermagen AB
    Inventors: Artur Schmidtchen, Martin Malmsten
  • Publication number: 20090312265
    Abstract: The invention relates to a molecule comprising at least the amino acid sequence K X K X1 X2 X K G X wherein X is any amino acid residue X1, and X2 is K or R and wherein said molecule have a length of from about 10 to about 100 amino acid residues or an analogue thereof The invention also relates to compositions comprising said molecule and use of the molecule and/or composition of the invention to combat microorganisms, such as bacteria, viruses, fungi, including yeast, and parasites.
    Type: Application
    Filed: February 12, 2007
    Publication date: December 17, 2009
    Applicant: Dermagen AB
    Inventors: Artur Schmidtchen, Martin Malmsten, Björn Walse
  • Publication number: 20090074864
    Abstract: The invention relates to an antimicrobial peptide with heparin binding activity, being derived from endogenous mammalian proteins being substantially free from antimicrobial activity selected from the group consisting of laminin isoforms, complement factor C3, histidin rich glycoprotein and kininogen and having from 10 to 36 amino acid residues, wherein the antimicrobial peptide consists of at least four amino acid residues selected from the group consisting of K, R and H. The invention also relates to pharmaceutical compositions comprising said antimicrobial peptide and use of the antimicrobial peptide and/or antimicrobial/pharmaceutical composition.
    Type: Application
    Filed: October 23, 2007
    Publication date: March 19, 2009
    Applicant: Dermagen AB
    Inventors: Artur Schmidtchen, Martin Malmsten
  • Publication number: 20080069849
    Abstract: The invention relates to the use of peptides, wherein at least one amino acid residue has been substituted to improve the efficacy of the antimicrobial peptide for the manufacturing of an antimicrobial composition. The composition can be used as a pharmaceutical composition to combat microorganisms, such as bacteria, virus, fungus, parasites as well as yeast.
    Type: Application
    Filed: November 17, 2005
    Publication date: March 20, 2008
    Applicant: Dermagen AB
    Inventors: Artur Schmidtchen, Martin Malmsten, Bjorn Walse
  • Publication number: 20070185019
    Abstract: The invention relates to an antimicrobial peptide with heparin binding activity, being derived from endogenous mammalian proteins being substantially free from antimicrobial activity selected from the group consisting of laminin isoforms, complement factor C3, histidin rich glycoprotein and kininogen and having from 10 to 36 amino acid residues, wherein the antimicrobial peptide consists of at least four amino acid residues selected from the group consisting of K, R and H. The invention also relates to pharmaceutical compositions comprising said antimicrobial peptide and use of the antimicrobial peptide and/or antimicrobial/pharmaceutical composition.
    Type: Application
    Filed: May 19, 2004
    Publication date: August 9, 2007
    Applicant: DERMAGEN AB
    Inventors: Artur Schmidtchen, Martin Malmsten