Abstract: Provided herein, in some embodiments, are rapid diagnostic tests comprising a lateral flow strip and an integrated swab head. The tests may be used to detect, for example, one or more pathogens, such as viral, bacterial, fungal, parasitic, or protozoan pathogens. Further embodiments provide methods of detecting genetic abnormalities. Nucleic acid tests using the diagnostic tests are provided.

Abstract: A reagent carrier includes: a cap configured to fit on an opening of a reaction vessel; and a reagent confined by the cap. The cap may be configured to release the reagent when a user manipulates the cap while the cap is fitted on the opening of the reaction vessel. For example, the reagent may be released when the user twists the cap from a first position to a second position or when the user pushes on a surface of the cap. The cap may be configured to seal the opening of the reaction vessel when the cap is fitted on the opening of the reaction vessel. In some implementations, the cap may be a blister cap containing the reagent. In some implementations, the cap may include a cage containing the reagent. In some implementations, the cap may include a deformable structure containing the reagent.

Abstract: Provided herein, in some embodiments, are rapid diagnostic tests to detect one or more target nucleic acid sequences (e.g., a nucleic acid sequence of one or more pathogens) having a seal component. In some embodiments, the pathogens are viral, bacterial, fungal, parasitic, or protozoan pathogens, such as SARS-CoV-2 or an influenza virus. Further embodiments provide methods of detecting genetic abnormalities. Diagnostic tests comprising a sample-collecting component, one or more reagents (e.g., lysis reagents, nucleic acid amplification reagents), a seal component, and a detection component (e.g., a component comprising a lateral flow assay strip and/or a colorimetric assay) are provided.

Abstract: Described herein in one embodiment is software, which may be downloaded to a device, to guide a user through administration of a test. Test results may be uploaded, manually or automatically, to a device or communicated remotely through a network. In an embodiment, the test is a rapid test. In an embodiment, the rapid test detects presence of COVID-19. In an embodiment, the rapid test detects COVID-19 or influenza. In an embodiment, the rapid test detects influenza A or influenza B. In an embodiment, the rapid test detects a target nucleic acid. In an embodiment, the target nucleic acid represents one of a viral, bacterial, fungal, parasitic or protozoan pathogen. Each of the rapid tests may be self administrable.

Abstract: Provided herein, in some embodiments, are rapid diagnostic tests to detect one or more target nucleic acid sequences (e.g., a nucleic acid sequence of one or more pathogens). In some embodiments, the pathogens are viral, bacterial, fungal, parasitic, or protozoan pathogens, such as SARS-CoV-2 or an influenza virus. Further embodiments provide methods of detecting genetic abnormalities. Diagnostic tests comprising a sample-collecting component, one or more reagents (e.g., lysis reagents, nucleic acid amplification reagents), and a detection component (e.g., a component comprising a lateral flow assay strip and/or a colorimetric assay) are provided.

Abstract: Described herein in one embodiment is a computer-implemented method comprising accessing information representing a detection component of a diagnostic test and determining, based at least in part on the information representing the detection component of the diagnostic test, results of the diagnostic test. Described herein in one embodiment is a method of performing a diagnostic test on a subject. In one embodiment, the method comprises obtaining a sample from the subject, processing the sample, analyzing the sample with a detection component of the diagnostic test, and performing a computer-implemented method comprising accessing information representing the detection component of a diagnostic test, and determining, based at least in part on the information representing the detection component of the diagnostic test, results of the diagnostic test.

Abstract: Provided herein are rapid diagnostic tests, systems, and methods for detecting one or more target nucleic acid sequences (e.g., a nucleic acid sequence of one or more pathogens, such as SARS-CoV-2 or an influenza virus) using isothermal nucleic acid amplification. The tests, systems, and methods described herein may be performed in a point-of-care setting or a home setting without specialized equipment.

Abstract: Apparatuses, methods, and systems for generating signatures based on sensing one or more gas concentration conditions are disclosed. One method includes sensing, by one or more sensors, levels of a gas over time for a plurality of gas concentration conditions, receiving, by a controller, the sensed levels of gas over time for the plurality of gas concentration conditions, and generating, by the controller, a plurality of signatures, wherein one or more signatures is generated for one or more gas concentration conditions based on the sensed levels of gas over time, and determining whether to take action or not to take action.

Abstract: A method of detecting and disabling offending devices includes monitoring for a radio frequency signal. When an offending device initializes and registers with a cell tower, it emits the radio frequency signal. After the radio frequency signal is detected, a message including an identification of the radio frequency signal is transmitted to a receiver of a base station. Responsive to receiving the message, the base station sends a secure transaction that includes an indication of the radio frequency signal to a processor of a cellular carrier system. Responsive to receiving the secure transaction, the processor of the cellular carrier system correlates a time and the radio frequency signal with an account associated with the registration of the offending device, disconnects from the offending device, and disables an account associated with the offending device.

Abstract: Apparatuses, methods, and systems for generating signatures based on sensing one or more gas concentration conditions are disclosed. One method includes sensing, by one or more sensors, levels of a gas over time for a plurality of gas concentration conditions, receiving, by a controller, the sensed levels of gas over time for the plurality of gas concentration conditions, and generating, by the controller, a plurality of signatures, wherein one or more signatures is generated for one or more gas concentration conditions based on the sensed levels of gas over time, and determining whether to take action or not to take action.

Abstract: Apparatuses, methods, and systems for detecting a substance are disclosed. One system includes a light source, an optical cavity, a cavity detector, and a processor. The light source generates a beam of electro-magnetic radiation, wherein a wavelength of the beam of electro-magnetic radiation is tuned to operate at multiple wavelengths. The optical cavity receives the beam of electro-magnetic radiation, wherein the physical characteristics of the cavity define a plurality of allowed axial-plus-transverse electro-magnetic radiation modes, wherein only a subset of the allowed axial-plus-transverse electro-magnetic radiation modes are excited when the optical cavity receives the beam of electro-magnetic radiation. The cavity detector senses electro-magnetic radiation emanating from the optical cavity.

Abstract: An auditing system (10) is provided for detecting at least one unauthorized operational activity in at least one website, and includes a processor coupled to at least one database (34) for storing data related to the at least one unauthorized operational activity. The processor is programmed to detect the at least one unauthorized operational activity in the at least one website using a monitoring module (22) configured to monitor the at least one website via a network (16) and provide unauthorized operational status information about the at least one website using a plurality of status messages generated based on the data, and a detection module (24) configured to examine the plurality of status messages and detect an anomaly caused by the at least one unauthorized operational activity.

Abstract: Apparatuses, methods, and systems for detecting a substance are disclosed. One system includes a light source, an optical cavity, a cavity detector, and a processor. The light source generates a beam of electro-magnetic radiation, wherein a wavelength of the beam of electro-magnetic radiation is tuned to operate at multiple wavelengths. The optical cavity receives the beam of electro-magnetic radiation, wherein the physical characteristics of the cavity define a plurality of allowed axial-plus-transverse electro-magnetic radiation modes, wherein only a subset of the allowed axial-plus-transverse electro-magnetic radiation modes are excited when the optical cavity receives the beam of electro-magnetic radiation. The cavity detector senses electro-magnetic radiation emanating from the optical cavity.

Abstract: Apparatuses, methods, and systems for detecting a substance are disclosed. One system includes a light source, an optical cavity, a cavity detector, and a processor. The light source generates a beam of electro-magnetic radiation, wherein a wavelength of the beam of electro-magnetic radiation is tuned to operate at multiple wavelengths. The optical cavity receives the beam of electro-magnetic radiation, wherein the physical characteristics of the cavity define a plurality of allowed axial-plus-transverse electro-magnetic radiation modes, wherein only a subset of the allowed axial-plus-transverse electro-magnetic radiation modes are excited when the optical cavity receives the beam of electro-magnetic radiation. The cavity detector senses electro-magnetic radiation emanating from the optical cavity.

Abstract: Apparatuses, methods, and systems for generating signatures based on sensing one or more gas concentration conditions are disclosed. One method includes sensing, by one or more sensors, levels of a gas over time for a plurality of gas concentration conditions, receiving, by a controller, the sensed levels of gas over time for the plurality of gas concentration conditions, and generating, by the controller, a plurality of signatures, wherein one or more signatures is generated for one or more gas concentration conditions based on the sensed levels of gas over time, and determining whether to take action or not to take action.

Abstract: Devices, systems and methods for detecting molecules in a solid state using UV lights in a dry condition are provided. Interaction between a plurality of molecules, a conformational change of a molecule, a size difference between a plurality of molecules and a presence of a molecule can be detected in a dry environment by measuring a light absorption in at least one of light transmission mode and light reflection mode. In a preferred embodiment, the measurement of a light absorption is performed at a wavelength of ultraviolet light between 260 nm and 285 nm.

Abstract: An auditing system (10) is provided for detecting at least one unauthorized operational activity in at least one website, and includes a processor coupled to at least one database (34) for storing data related to the at least one unauthorized operational activity. The processor is programmed to detect the at least one unauthorized operational activity in the at least one website using a monitoring module (22) configured to monitor the at least one website via a network (16) and provide unauthorized operational status information about the at least one website using a plurality of status messages generated based on the data, and a detection module (24) configured to examine the plurality of status messages and detect an anomaly caused by the at least one unauthorized operational activity.

Abstract: An auditing system (10) is provided for detecting at least one unauthorized operational activity in at least one website, and includes a processor coupled to at least one database (34) for storing data related to the at least one unauthorized operational activity. The processor is programmed to detect the at least one unauthorized operational activity in the at least one website using a monitoring module (22) configured to monitor the at least one website via a network (16) and provide unauthorized operational status information about the at least one website using a plurality of status messages generated based on the data, and a detection module (24) configured to examine the plurality of status messages and detect an anomaly caused by the at least one unauthorized operational activity.

Abstract: Apparatuses, methods, and systems for detecting a substance are disclosed. One system includes a light source, an optical cavity, a cavity detector, and a processor. The light source generates a beam of electro-magnetic radiation, wherein a wavelength of the beam of electro-magnetic radiation is tuned to operate at multiple wavelengths. The optical cavity receives the beam of electro-magnetic radiation, wherein the physical characteristics of the cavity define a plurality of allowed axial-plus-transverse electro-magnetic radiation modes, wherein only a subset of the allowed axial-plus-transverse electro-magnetic radiation modes are excited when the optical cavity receives the beam of electro-magnetic radiation. The cavity detector senses electro-magnetic radiation emanating from the optical cavity.

Abstract: A rotational antenna includes a stationary feed which is disposed in a substantially vertical orientation. A parabolic dish is rotationally mounted about the stationary feed in a state of being tipped with respect to the stationary, substantially vertically oriented feed. The rotational parabolic antenna may alternatively be provided with a rotating radio frequency (RF) and acoustic feed. Other embodiments are disclosed.