Abstract: The compound 4'-(9-[4-[N-methyl-carboxamido]-5-methyl]acridinylamino)methanesulphon-m-a nisidide and acid addition salts thereof have antitumor properties.

Abstract: A distance indicating device comprises a probe having therein a light source and light sensitive element to receive light reflected from the surroundings of the probe. A reference point is movable relative to the probe. The light sensitive element gives rise to an electric signal. A first storage means stores a signal representing the maximum reflected light returned to the light sensitive element. A second storage means stores a signal representing the light returned to the light sensitive element representing the minimum reflected light. A selection means selects a signal level between the maximum and minimum stored signals' and a measuring element measures the distance between the reference point and a further reference point, associated with the probe, when the signal level reaches the selected signal level.

Abstract: The invention relates to the carbonylation of cross linked substituted and unsubstituted polysaccharides, their copolymers with macroporous synthetic polymers, macroporous synthetic polymers and rigid supports with pendant hydroxyalkyl groups. The carbonylated product can be used to prepare an affinity chromatography matrix which remains an uncharged species at varying pH's. The carbonylated product is also useful for the preparation of other compounds: Typical polysaccharides are agarose, starch, dextran, cellulose and regenerated cellulose, typical macroporous synthetic polymers are acrylamides, acrylates and methacrylates, typical rigid supports are silica beads coated with hydroxy alkyl groups and typical cabonylating agents are N,N'-carbonyl diimidazole; N,N'carbonyl di-1,2,3-benzotriazole; and N,N'-carbonyl di-1,2,4-triazole.

Abstract: Carbonylation of a polysaccharide and the product of that carbonylation. The carbonylated product can be used to prepare an affinity chromatography matrix which is an uncharged species of varying pH's. The carbonylated product is also useful for the preparation of other compounds. Typical polysaccharides are agarose, starch, dextran, cellulose and regenerated cellulose and typical carbonylating agents are N,N'-carbonyl diimidazole; N,N' carbonyl di-1,2,3-benzotriazole; and N,N'-carbonyl di-1,2,4-triazole.

Abstract: A mechanical attenuating system for preventing horizontal forces from being transmitted from a base such as the ground to a structure such as a building or a nuclear reactor resting on that base. The system has two components: a vertical support which allows free relative horizontal movement between structure and base, and horizontal damping. The two can be combined into a single instrument. When the two are used separately, the support may be supplied by rubber or rolling bearings, by flexible columns or by tendons.

Abstract: The invention relates to a novel sulphated cationic ion exchanger and to a method for preparation thereof. In addition it relates to a method of improving the capacity of an exchange matrix to receive sulphated groups. Although the general attraction of sulphate groups to proteins is known we have found that sulphated ion exchangers selectively bind lipoproteins in blood serum or plasma under suitable conditions. We have also discovered that when hydroxyalkyl groups are introduced into the ion exchanger matrix its capacity for taking up sulphate groups is unexpectedly increased. A method of use of the ion exchanger is also described.

Abstract: The invention relates to a novel water insoluble hydroxyalkylated cross-linked regenerated cellulose and a method for its preparation. The product is characterized by having outstanding swelling characteristics and high chemical reactivity. A method of preparing the product using near stoichiometric proportions of reagents is described. Use of the product directly in gel chromatography and as an intermediate in the preparation of ion exchangers is described.

Abstract: This spinning machine weighs about 10 lbs. and is of about the size of a one foot cube. The reel on which the spun yarn is to be stored is contained within a large horizontal tube. The yarn is fed through a hole in the wall of the tube from a groove on the outer surface. The reel is rotated by running on the inner surface of the tube which is driven by, for instance, a sewing machine motor. By control of dimensions or by braking a relative speed is imposed between the reel and the tube and is the speed for reeling yarn. The yarn is fed to the groove from two small tubes, one stationary and the other rotating with the large tube. Both are coaxial with the large tube. Locks or sliver to be spun are presented to a surface with saw-tooth corrugations alternating with slots, and is fed to the stationary small tube.

Abstract: A panel type absorber of radiant energy, applicable in particular as a solar collector, is formed of two shallow trays sealed together as a box. Energy absorbed at one face is conveyed by convection of a primary fluid to a heat exchanger integral with the box and consisting of one or more pipes, horizontal or vertical, which convey a secondary fluid to be heated. Air is excluded from the primary fluid to minimize corrosion.