Patents Assigned to DEZHOU UNIVERSITY
  • Publication number: 20240010470
    Abstract: A multifunctional suspension device for mechanical engineering, relating to mechanical engineering equipment.
    Type: Application
    Filed: July 7, 2022
    Publication date: January 11, 2024
    Applicant: DEZHOU UNIVERSITY
    Inventors: Haorui LIU, Juan YANG, Shida LIU, Changkun ZHANG, Yayu CHEN
  • Patent number: 11332707
    Abstract: An endophytic fungus from gingko, that is, Fusarium proliferatum DZHQ1 having antitumor activity and antibacterial activity, is isolated from the ginkgo bark. The species of the strain is determined by the combination of colonial morphology and 18 sRNA sequencing, and then the anti-cervical cancer activity of a crude extract of the strain is detected by MTT. Finally, a secondary metabolite of the strain with an inhibition rate of more than 50% is isolated by semi-preparative HPLC, which promotes the further screening of individual compounds with anti-tumor activity. Moreover, the metabolite of the endophytic fungus from gingko shows a more pronounced inhibition in the detection of activity against E. coli and/or S. aureus, and has potential use in the preparation of new antibacterial products.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: May 17, 2022
    Assignee: DEZHOU UNIVERSITY
    Inventors: Qing He, Qiangcheng Zeng, Lianying Zhang, Zhongmin Dai, Haixia Zhou, Mingyou Wang, Jianzhou Meng
  • Publication number: 20210238538
    Abstract: An endophytic fungus from gingko, that is, Fusarium proliferatum DZHQ1 having antitumor activity and antibacterial activity, is isolated from the ginkgo bark. The species of the strain is determined by the combination of colonial morphology and 18 sRNA sequencing, and then the anti-cervical cancer activity of a crude extract of the strain is detected by MTT. Finally, a secondary metabolite of the strain with an inhibition rate of more than 50% is isolated by semi-preparative HPLC, which promotes the further screening of individual compounds with anti-tumor activity. Moreover, the metabolite of the endophytic fungus from gingko shows a more pronounced inhibition in the detection of activity against E. coli and/or S. aureus, and has potential use in the preparation of new antibacterial products.
    Type: Application
    Filed: November 2, 2018
    Publication date: August 5, 2021
    Applicant: DEZHOU UNIVERSITY
    Inventors: Qing HE, Qiangcheng ZENG, Lianying ZHANG, Zhongmin DAI, Haixia ZHOU, Mingyou WANG, Jianzhou MENG
  • Publication number: 20190178837
    Abstract: A sensing device and method in detecting binding energy and binding kinetics between molecules; the sensing device has a sensor, a microfluidic chip and a measurement circuit. The sensor has multiple field effect transistors, and each field effect transistor adopts single-layer single crystal graphene as a conductive channel, thereby having extremely high sensitivity and stability; and the field effect transistors are arranged in an array and are provided with multichannel measurement circuits to detect the binding dynamics processes of different molecules or different copies of the same molecule in parallel so as to meet the high-throughput detection requirements. A compound that is non-covalently bound with the single-layer single crystal graphene as a medium to fix probe molecules on the surface of the conductive channel, thereby retaining the intrinsic structure of the graphene, and improving the signal-to-noise ratio and the sensitivity of the graphene field effect transistor.
    Type: Application
    Filed: November 30, 2016
    Publication date: June 13, 2019
    Applicant: DEZHOU UNIVERSITY
    Inventors: Shicai XU, Jian ZHAN, Jihua WANG, Yaoqi ZHOU