Patents Assigned to Diamond Scientific Co.
  • Method of blood component decontamination by glucose addition
    Patent number: 5176921
    Abstract: Biological compositions are freed of functional polynucletides by treatment of the biological composition with psoralen derivatives under irradiation conditions in which the proteins retain their original physiological activities and any polynucleotide present is rendered inactive. More specifically blood components are decontaminated of viruses by the addition of psoralen and irradiation and thereafter adding glucose.
    Type: Grant
    Filed: May 11, 1989
    Date of Patent: January 5, 1993
    Assignees: Diamond Scientific Co., University of California
    Inventors: Gary P. Wiesehahn, Laurence Corash
  • Preparation of inactivated viral vaccines
    Patent number: 5106619
    Abstract: Vaccines employing inactivated viruses having improved retention of antigenic characteristics are prepared by psoralen-inactivation of the live virus in a non-oxidizing atmosphere. By excluding oxygen and other oxidizing species from the inactivation medium, degradation of the antigen characteristics resulting from irradiation with ultraviolet light is largely prevented. The resulting inactivated viruses are employed in vaccine preparations for the inoculation of susceptible hosts to inhibit viral infection.
    Type: Grant
    Filed: January 10, 1990
    Date of Patent: April 21, 1992
    Assignee: Diamond Scientific Co.
    Inventors: Gary P. Wiesehahn, Richard P. Creagan, David R. Stevens, Richard Giles
  • Syringe
    Patent number: 4863433
    Abstract: A syringe is provided which has a barrel, a plunger having a hollow center, with the needle stored in the hollow center. A storage compartment is used to encase the needle and keep it sterile while being stored within the plunger. A cap on the tip of the barrel having a protruding shoulder securely engages the tip of the barrel while being stored, and assists in preventing leakage of inoculant from the barrel of the syringe.
    Type: Grant
    Filed: May 23, 1988
    Date of Patent: September 5, 1989
    Assignee: Diamond Scientific Co.
    Inventors: John B. Payne, Davis R. Jones
  • FVR vaccine
    Patent number: 4791062
    Abstract: Novel vaccines for feline viral rhinotracheitis are prepared by psoralen inactivation of live Feline Herpesvirus I by exposure to ultraviolet radiation in the presence of an inactivating furocoumarin. The resulting inactivated viruses are suitable as the immunogenic substances in vaccines, which vaccines are useful for inoculation of hosts susceptible to feline virus rhinotracheitis.
    Type: Grant
    Filed: July 6, 1987
    Date of Patent: December 13, 1988
    Assignee: Diamond Scientific Co.
    Inventors: Gary P. Wiesehahn, Richard E. Giles, David R. Stevens
  • Photochemical decontamination treatment of whole blood or blood components
    Patent number: 4748120
    Abstract: Biological compositions are freed of functional polynucleotides by treatment of the biological composition with psoralen derivatives under irradiation conditions in which the proteins retain their original physiological activities and any polynucleotide present is rendered inactive.
    Type: Grant
    Filed: October 20, 1986
    Date of Patent: May 31, 1988
    Assignee: Diamond Scientific Co.
    Inventor: Gary P. Wiesehahn
  • Photochemical decontamination treatment of whole blood or blood components
    Patent number: 4727027
    Abstract: Biological compositions are decontaminated by treatment with furocoumarin derivatives and irradiation under particular conditions in which the proteins retain their original physiological activities and any pathogenic microorganisms and polynucleotide fragments thereof are rendered inactive. It has been found that reduction of the amount of dissolved oxygen in the treatment solution substantially inhibits denaturation of the proteins.
    Type: Grant
    Filed: October 7, 1985
    Date of Patent: February 23, 1988
    Assignee: Diamond Scientific Co.
    Inventors: Gary P. Wiesehahn, Richard P. Creagan
  • Disposable syringe housing
    Patent number: D323391
    Type: Grant
    Filed: May 10, 1988
    Date of Patent: January 21, 1992
    Assignee: Diamond Scientific Co.
    Inventors: John B. Payne, David R. Jones