Abstract: Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.
Type:
Grant
Filed:
December 31, 2011
Date of Patent:
December 4, 2012
Assignee:
Diazem Corporation
Inventors:
Charles E. Skinner, William Henry Campbell, Yung K. Kim
Abstract: Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.
Type:
Grant
Filed:
May 2, 2008
Date of Patent:
February 14, 2012
Assignee:
Diazem Corporation
Inventors:
Charles E. Skinner, William Henry Campbell, Yung K. Kim
Abstract: Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.
Type:
Application
Filed:
November 13, 2006
Publication date:
April 5, 2007
Applicant:
Diazem Corporation
Inventors:
Charles Skinner, William Campbell, Yung Kim
Abstract: Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.
Type:
Grant
Filed:
June 7, 2004
Date of Patent:
January 2, 2007
Assignee:
Diazem Corporation
Inventors:
William H. Campbell, Yung K. Kim, Charles E. Skinner
Abstract: The present invention provides a silicone derivatized macromolecule that is supported on a particulate support or a separation membrane and method for making that composition. The silicon-derivatized macromolecule can also be combined with chiral ligands or chelated metals. The applications for the silicone derivatized macromolecule variety including use in HPLC separations, in purification process and in personal care formulations.
Type:
Application
Filed:
June 27, 2006
Publication date:
October 26, 2006
Applicant:
DIAZEM CORPORATION
Inventors:
Yung Kim, David Karpovich, William Campbell, Ling Yang
Abstract: Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.
Type:
Application
Filed:
June 7, 2004
Publication date:
November 11, 2004
Applicant:
Diazem Corporation
Inventors:
William Henry Campbell, Yung K. Kim, Charles E. Skinner
Abstract: A bonded phase material useful with a chromatographic separation process. The bonded phase material includes a hydroxyl bearing porous material, a first controlled stoichiometric amount of a first interactive silane covalently bonded to the surface of the hydroxyl bearing porous material and at least one additional interactive silane covalently bonded to the surface of the hydroxyl bearing porous material to provide the porous material with a gradient of functionality of varied polarity creates a unique overall polarity which is not obtainable by the separate interactive silanes themselves. The method of silating the porous material includes sequential application of controlled stoichiometric amounts of the interactive silanes.