Patents Assigned to Digene Diagnostics, Inc.
  • Continuous amplification reaction
    Patent number: 5981179
    Abstract: Continuous amplification reaction provide a method of amplifying a specific nucleic acid without the need to cycle a reaction. The method produces RNA transcripts which can be detected by a variety of methods. Amplification and detection kits are also provided.
    Type: Grant
    Filed: September 14, 1995
    Date of Patent: November 9, 1999
    Assignee: Digene Diagnostics, Inc.
    Inventors: Attila T. Lorinez, Abel DeLaRosa
  • Highly sensitive method for detecting peroxidase
    Patent number: 5116734
    Abstract: The present invention is directed to a composition of matter and a process for detecting the presence of an oxidative catalyst in a biological sample. The composition comprises a precipitate formed by oxidation of a chromogenic substrate in the presence of the catalyst, together with two or more co-precipitated metals. A strong signal is formed with which to detect an oxidation catalyst which is localized to a target molecule. Target molecules may be nucleic acids, antibodies or cell surface antigens.
    Type: Grant
    Filed: October 25, 1991
    Date of Patent: May 26, 1992
    Assignee: Digene Diagnostics, Inc.
    Inventors: Thomas W. Higgs, Floyd E. Taub