Abstract: A feed supplement for ruminants comprising a gluconeogenic compound, which can be digested in the rumen and a hydrogenated fatty acid, which is rumen inert, is described. One example of such a feed supplement comprises 30% gluconeogenic compounds, by weight and 30% C.sub.14 -C.sub.22 hydrogenated fatty acids by weight, the balance being essentially inert compounds. The feed supplement of the present invention can be used in the treatment of or for the prevention of negative energy or a nutrient imbalance. A method of treating or preventing a nutrient imbalance by administering to a ruminant in need thereof, a daily dosage amount of a composition comprising a gluconeogenic compound, which can be digested in the rumen and a hydrogenated fatty acid, which is rumen inert, for from 10-21 days prior to calving to 21-42 days after calving.