Patents Assigned to Donald Danforth Plant Science Center
  • Publication number: 20130310585
    Abstract: The present invention provides a new and improved method for increasing plant seed oil content by seed-specific manipulation of PLD ? expression The inventive method is applicable to a variety of plant species, such as Arabidopsis, camelina, and soybean, and has the potential to increase seed oil content (both dietary and industrial) and vegetable oil production in crops.
    Type: Application
    Filed: October 19, 2011
    Publication date: November 21, 2013
    Applicants: DONALD DANFORTH PLANT SCIENCE CENTER, THE CURATORS OF UNIVERSITY OF MISSOURI-ST. LOUIS
    Inventors: Xuemin Wang, Maoyin Li, Geliang Wang
  • Patent number: 8558057
    Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: October 15, 2013
    Assignee: Donald Danforth Plant Science Center
    Inventors: Dilip Maganial Shah, Anita K. Snyder
  • Publication number: 20130145495
    Abstract: This invention provides genetically modified photosynthetic organisms and methods and constructs for enhancing inorganic carbon fixation. A photosynthetic organism of the present invention comprises a RUBISCO fusion protein operatively coupled to a protein-protein interaction domain to enable the functional association of RUBISCO and carbonic anhydrase.
    Type: Application
    Filed: April 25, 2011
    Publication date: June 6, 2013
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventor: Richard T. Sayre
  • Publication number: 20130117880
    Abstract: Transgenic plants expressing the KP4 antifungal protein are provided which exhibit high levels of antifungal resistance. Such transgenic plants contain a recombinant DNA construct comprising a heterologous signal peptide sequence that is oper ably linked to a non-native nucleic acid sequence encoding a mature KP4 antifungal protein.
    Type: Application
    Filed: July 20, 2011
    Publication date: May 9, 2013
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventors: Thomas James Smith, Dilip Shah
  • Publication number: 20120180160
    Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.
    Type: Application
    Filed: March 26, 2012
    Publication date: July 12, 2012
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventors: Dilip Maganial Shah, Anita Kay Snyder
  • Publication number: 20120164177
    Abstract: The present invention relates generally to peptide vaccines. More specifically, the present invention relates to vaccines against rhinoviruses and other related and non-related pathogenic animal viruses. In addition, the present invention relates generally to methods of designing and producing vaccines against viruses and, in certain embodiments, against rhinoviruses and other pathogenic viruses.
    Type: Application
    Filed: March 13, 2012
    Publication date: June 28, 2012
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventors: Thomas J. Smith, Umesh C. Katpally
  • Patent number: 8163979
    Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: April 24, 2012
    Assignee: Donald Danforth Plant Science Center
    Inventors: Dilip Maganlal Shah, Anita Kay Snyder
  • Patent number: 8153760
    Abstract: The present invention relates generally to peptide vaccines. More specifically, the present invention relates to vaccines against rhinoviruses and other related and non-related pathogenic animal viruses. In addition, the present invention relates generally to methods of designing and producing vaccines against viruses and, in certain embodiments, against rhinoviruses and other pathogenic viruses.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: April 10, 2012
    Assignee: Donald Danforth Plant Science Center
    Inventors: Thomas J. Smith, Umesh C. Katpally
  • Publication number: 20110010802
    Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.
    Type: Application
    Filed: September 21, 2010
    Publication date: January 13, 2011
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventors: Dilip Maganlal Shah, Anita Kay Snyder
  • Publication number: 20100313307
    Abstract: A transgenic dicotyledonous plant having a deficiency of one or more plant seed storage proteins, further having a transgenic polynucleotide construct comprising an open reading frame operably linked to a storage protein promoter and an ER signal sequence. The polynucleotide construct encodes a protein product that can accumulate at high levels in the seed. Also provided are methods of producing a heterologous protein in a plant seed.
    Type: Application
    Filed: June 28, 2009
    Publication date: December 9, 2010
    Applicants: DONALD DANFORTH PLANT SCIENCE CENTER, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
    Inventors: ELIOT M. HERMAN, MONICA A. SCHMIDT
  • Patent number: 7847064
    Abstract: Novel chimeric plant promoter sequences are provided, together with plant gene expression cassettes comprising such sequences. In certain preferred embodiments, the chimeric plant promoters comprise the BoxII cis element and/or derivatives thereof. In addition, novel transcription factors are provided, together with nucleic acid sequences encoding such transcription factors and plant gene expression cassettes comprising such nucleic acid sequences. In certain preferred embodiments, the novel transcription factors comprise the acidic domain, or fragments thereof, of the RF2a transcription factor. Methods for using the chimeric plant promoter sequences and novel transcription factors in regulating the expression of at least one gene of interest are provided, together with transgenic plants comprising such chimeric plant promoter sequences and novel transcription factors.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: December 7, 2010
    Assignee: Donald Danforth Plant Science Center
    Inventors: Roger N. Beachy, Maria Isabel Ordiz Luis, Shunhong Dai
  • Patent number: 7825297
    Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: November 2, 2010
    Assignee: Donald Danforth Plant Science Center
    Inventors: Dilip Maganlal Shah, Anita Kay Snyder
  • Patent number: 7767428
    Abstract: This invention provides a salutaridinol 7-O-acetyltransferase protein, a salutaridinol 7-O-acetyltransferase gene, and a sequence which is complementary thereto. This invention further provides a method for the production of thebaine comprising the steps of (i) contacting in vitro a protein having salutaridinol 7-O-acetyltransferase activity with salutaridinol and acetyl coenzyme A at pH 8 to 9, and (ii) recovering the thebaine thus produced.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: August 3, 2010
    Assignee: Donald Danforth Plant Science Center
    Inventors: Toni M. Kutchan, Meinhart H. Zenk, Torsten Grothe
  • Publication number: 20100075385
    Abstract: The present invention relates to methyl transfer enzymes involved in alkaloid biosynthesis in opium poppy. More particularly, the invention relates to proteins having (R,S)-reticuline 7-O-methyltransferase activity, to proteins having (R,S)-norcoclaurine 6-O-methyltransferase activity and to derivatives and analogues of these proteins. The invention also relates to nucleic acid molecules encoding the proteins, and their derivatives and analogues, and to their use in the production of methylated catechols and tetrahydrobenzylisoquinolines.
    Type: Application
    Filed: February 24, 2009
    Publication date: March 25, 2010
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventors: Toni M. Kutchan, Anan Ounaroon, Susanne Frick, Stefanie Haase-Fernando
  • Publication number: 20100037351
    Abstract: Transgenic plants and seeds with altered expression of phospholipase D? (PLD?) are described, i.e., plants and seeds either overexpressing or underexpressing PLD?. Methods for producing such transgenic plants and for increasing a plant's ability to capture and utilize nitrogen, increasing a plant's biomass production, increasing the yield of a plant or increasing a plant's ability to grow under hyperosmotic stress by overexpressing PLD? are also disclosed. Further disclosed are transgenic plants and seeds which overexpress phospholipase D alpha3 (PLD?3), methods for producing such transgenic plants and seeds, and methods for increasing a plant's ability to grow under hyperosmotic stress by overexpressing phospholipase D alpha3.
    Type: Application
    Filed: March 27, 2009
    Publication date: February 11, 2010
    Applicants: DONALD DANFORTH PLANT SCIENCE CENTER, THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: Xuemin Wang, Yueyun Hong
  • Patent number: 7517689
    Abstract: Novel chimeric plant promoter sequences are provided, together with plant gene expression cassettes comprising such sequences. Novel transcription factors are provided, together with nucleic acid sequences encoding such transcription factors and plant gene expression cassettes comprising such nucleic acid sequences. Methods for using the chimeric plant promoter sequences and novel transcription factors in regulating the expression of at least one gene of interest are provided, together with transgenic plants comprising such chimeric plant promoter sequences and novel transcription factors.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: April 14, 2009
    Assignee: Donald Danforth Plant Science Center
    Inventors: Roger N. Beachy, Shunhong Dai, Maria Isabel Ordiz Luis
  • Patent number: 7514251
    Abstract: The present invention relates to methyl transfer enzymes involved in alkaloid biosynthesis in opium poppy. More particularly, the invention relates to proteins having (R,S)-reticuline 7-O-methyltransferase activity, to proteins having (R,S)-norcoclaurine 6-O-methyltransferase activity and to derivatives and analogues of these proteins. The invention also relates to nucleic acid molecules encoding the proteins, and their derivatives and analogues, and to their use in the production of methylated catechols and tetrahydrobenzylisoquinolines.
    Type: Grant
    Filed: July 8, 2004
    Date of Patent: April 7, 2009
    Assignee: Donald Danforth Plant Science Center
    Inventors: Toni M. Kutchan, Anan Ounaroon, Stefanie Haase, Susanne Frick
  • Publication number: 20090053764
    Abstract: This invention provides a protein comprising consecutive amino acids, the amino acid sequence of which is illustrated in FIG. 8 (SEQ. ID No. 14) or, a fragment thereof having at least 15 amino acids, or a variant thereof, the sequence of which has at least 70% identity with the amino acid sequence of FIG. 8 (SEQ. ID No. 14) over a length of at least 400 amino acids. This invention further provides a peptide comprising a fragment of salutaridinol 7-O-acetyltransferase protein of at least 6 consecutive amino acids which is not present in other plant acetyltransferases as illustrated in FIG. 2 (SEQ. IDs No. 8 to 12). This invention further provides a nucleic acid molecule comprising consecutive nucleotides (i) the nucleic acid sequence of which is illustrated in FIG. 9 (SEQ. ID No. 13) or FIG. 10 (SEQ. ID No. 15), or (ii) a fragment thereof having a length of at least 45 nucleotides, or (iii) a variant thereof, the sequence of which has at least 70% identity with the sequence of FIG. 9 (SEQ. ID No. 13) or FIG.
    Type: Application
    Filed: May 15, 2008
    Publication date: February 26, 2009
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventors: Toni M. Kutchan, Meinhart H. Zenk, Torsten Grothe
  • Publication number: 20080201800
    Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.
    Type: Application
    Filed: December 20, 2007
    Publication date: August 21, 2008
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventors: Dilip Maganlal Shah, Anita Kay Snyder
  • Publication number: 20080196124
    Abstract: Methods for obtaining plants with decreased responses to auxins by reducing exprssion of endogenous MYB77 genes in plants are disclosed. Also disclosed are methods of using plant MYB77 transcriptional promoter sequences to drive expression of heterologous genes in select plant cells at select times in plant development. Methods of obtaining plants with decreased lateral root formation when grown under nutrient deficient conditions by reducing expression of endogenous MYB77 and transgenic plants with reduced expression of endogenous MYB77 genes in are also provided.
    Type: Application
    Filed: April 27, 2007
    Publication date: August 14, 2008
    Applicant: DONALD DANFORTH PLANT SCIENCE CENTER
    Inventors: Daniel P. Schachtman, Ryoung Shin