Patents Assigned to Donald Danforth Plant Science Center
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Publication number: 20130310585Abstract: The present invention provides a new and improved method for increasing plant seed oil content by seed-specific manipulation of PLD ? expression The inventive method is applicable to a variety of plant species, such as Arabidopsis, camelina, and soybean, and has the potential to increase seed oil content (both dietary and industrial) and vegetable oil production in crops.Type: ApplicationFiled: October 19, 2011Publication date: November 21, 2013Applicants: DONALD DANFORTH PLANT SCIENCE CENTER, THE CURATORS OF UNIVERSITY OF MISSOURI-ST. LOUISInventors: Xuemin Wang, Maoyin Li, Geliang Wang
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Patent number: 8558057Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.Type: GrantFiled: March 26, 2012Date of Patent: October 15, 2013Assignee: Donald Danforth Plant Science CenterInventors: Dilip Maganial Shah, Anita K. Snyder
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Publication number: 20130145495Abstract: This invention provides genetically modified photosynthetic organisms and methods and constructs for enhancing inorganic carbon fixation. A photosynthetic organism of the present invention comprises a RUBISCO fusion protein operatively coupled to a protein-protein interaction domain to enable the functional association of RUBISCO and carbonic anhydrase.Type: ApplicationFiled: April 25, 2011Publication date: June 6, 2013Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventor: Richard T. Sayre
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Publication number: 20130117880Abstract: Transgenic plants expressing the KP4 antifungal protein are provided which exhibit high levels of antifungal resistance. Such transgenic plants contain a recombinant DNA construct comprising a heterologous signal peptide sequence that is oper ably linked to a non-native nucleic acid sequence encoding a mature KP4 antifungal protein.Type: ApplicationFiled: July 20, 2011Publication date: May 9, 2013Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventors: Thomas James Smith, Dilip Shah
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Publication number: 20120180160Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.Type: ApplicationFiled: March 26, 2012Publication date: July 12, 2012Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventors: Dilip Maganial Shah, Anita Kay Snyder
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Publication number: 20120164177Abstract: The present invention relates generally to peptide vaccines. More specifically, the present invention relates to vaccines against rhinoviruses and other related and non-related pathogenic animal viruses. In addition, the present invention relates generally to methods of designing and producing vaccines against viruses and, in certain embodiments, against rhinoviruses and other pathogenic viruses.Type: ApplicationFiled: March 13, 2012Publication date: June 28, 2012Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventors: Thomas J. Smith, Umesh C. Katpally
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Patent number: 8163979Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.Type: GrantFiled: September 21, 2010Date of Patent: April 24, 2012Assignee: Donald Danforth Plant Science CenterInventors: Dilip Maganlal Shah, Anita Kay Snyder
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Patent number: 8153760Abstract: The present invention relates generally to peptide vaccines. More specifically, the present invention relates to vaccines against rhinoviruses and other related and non-related pathogenic animal viruses. In addition, the present invention relates generally to methods of designing and producing vaccines against viruses and, in certain embodiments, against rhinoviruses and other pathogenic viruses.Type: GrantFiled: January 17, 2006Date of Patent: April 10, 2012Assignee: Donald Danforth Plant Science CenterInventors: Thomas J. Smith, Umesh C. Katpally
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Publication number: 20110010802Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.Type: ApplicationFiled: September 21, 2010Publication date: January 13, 2011Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventors: Dilip Maganlal Shah, Anita Kay Snyder
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Publication number: 20100313307Abstract: A transgenic dicotyledonous plant having a deficiency of one or more plant seed storage proteins, further having a transgenic polynucleotide construct comprising an open reading frame operably linked to a storage protein promoter and an ER signal sequence. The polynucleotide construct encodes a protein product that can accumulate at high levels in the seed. Also provided are methods of producing a heterologous protein in a plant seed.Type: ApplicationFiled: June 28, 2009Publication date: December 9, 2010Applicants: DONALD DANFORTH PLANT SCIENCE CENTER, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTUREInventors: ELIOT M. HERMAN, MONICA A. SCHMIDT
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Patent number: 7847064Abstract: Novel chimeric plant promoter sequences are provided, together with plant gene expression cassettes comprising such sequences. In certain preferred embodiments, the chimeric plant promoters comprise the BoxII cis element and/or derivatives thereof. In addition, novel transcription factors are provided, together with nucleic acid sequences encoding such transcription factors and plant gene expression cassettes comprising such nucleic acid sequences. In certain preferred embodiments, the novel transcription factors comprise the acidic domain, or fragments thereof, of the RF2a transcription factor. Methods for using the chimeric plant promoter sequences and novel transcription factors in regulating the expression of at least one gene of interest are provided, together with transgenic plants comprising such chimeric plant promoter sequences and novel transcription factors.Type: GrantFiled: February 3, 2006Date of Patent: December 7, 2010Assignee: Donald Danforth Plant Science CenterInventors: Roger N. Beachy, Maria Isabel Ordiz Luis, Shunhong Dai
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Patent number: 7825297Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.Type: GrantFiled: December 20, 2007Date of Patent: November 2, 2010Assignee: Donald Danforth Plant Science CenterInventors: Dilip Maganlal Shah, Anita Kay Snyder
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Patent number: 7767428Abstract: This invention provides a salutaridinol 7-O-acetyltransferase protein, a salutaridinol 7-O-acetyltransferase gene, and a sequence which is complementary thereto. This invention further provides a method for the production of thebaine comprising the steps of (i) contacting in vitro a protein having salutaridinol 7-O-acetyltransferase activity with salutaridinol and acetyl coenzyme A at pH 8 to 9, and (ii) recovering the thebaine thus produced.Type: GrantFiled: May 15, 2008Date of Patent: August 3, 2010Assignee: Donald Danforth Plant Science CenterInventors: Toni M. Kutchan, Meinhart H. Zenk, Torsten Grothe
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Publication number: 20100075385Abstract: The present invention relates to methyl transfer enzymes involved in alkaloid biosynthesis in opium poppy. More particularly, the invention relates to proteins having (R,S)-reticuline 7-O-methyltransferase activity, to proteins having (R,S)-norcoclaurine 6-O-methyltransferase activity and to derivatives and analogues of these proteins. The invention also relates to nucleic acid molecules encoding the proteins, and their derivatives and analogues, and to their use in the production of methylated catechols and tetrahydrobenzylisoquinolines.Type: ApplicationFiled: February 24, 2009Publication date: March 25, 2010Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventors: Toni M. Kutchan, Anan Ounaroon, Susanne Frick, Stefanie Haase-Fernando
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Publication number: 20100037351Abstract: Transgenic plants and seeds with altered expression of phospholipase D? (PLD?) are described, i.e., plants and seeds either overexpressing or underexpressing PLD?. Methods for producing such transgenic plants and for increasing a plant's ability to capture and utilize nitrogen, increasing a plant's biomass production, increasing the yield of a plant or increasing a plant's ability to grow under hyperosmotic stress by overexpressing PLD? are also disclosed. Further disclosed are transgenic plants and seeds which overexpress phospholipase D alpha3 (PLD?3), methods for producing such transgenic plants and seeds, and methods for increasing a plant's ability to grow under hyperosmotic stress by overexpressing phospholipase D alpha3.Type: ApplicationFiled: March 27, 2009Publication date: February 11, 2010Applicants: DONALD DANFORTH PLANT SCIENCE CENTER, THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Xuemin Wang, Yueyun Hong
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Patent number: 7517689Abstract: Novel chimeric plant promoter sequences are provided, together with plant gene expression cassettes comprising such sequences. Novel transcription factors are provided, together with nucleic acid sequences encoding such transcription factors and plant gene expression cassettes comprising such nucleic acid sequences. Methods for using the chimeric plant promoter sequences and novel transcription factors in regulating the expression of at least one gene of interest are provided, together with transgenic plants comprising such chimeric plant promoter sequences and novel transcription factors.Type: GrantFiled: July 9, 2004Date of Patent: April 14, 2009Assignee: Donald Danforth Plant Science CenterInventors: Roger N. Beachy, Shunhong Dai, Maria Isabel Ordiz Luis
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Patent number: 7514251Abstract: The present invention relates to methyl transfer enzymes involved in alkaloid biosynthesis in opium poppy. More particularly, the invention relates to proteins having (R,S)-reticuline 7-O-methyltransferase activity, to proteins having (R,S)-norcoclaurine 6-O-methyltransferase activity and to derivatives and analogues of these proteins. The invention also relates to nucleic acid molecules encoding the proteins, and their derivatives and analogues, and to their use in the production of methylated catechols and tetrahydrobenzylisoquinolines.Type: GrantFiled: July 8, 2004Date of Patent: April 7, 2009Assignee: Donald Danforth Plant Science CenterInventors: Toni M. Kutchan, Anan Ounaroon, Stefanie Haase, Susanne Frick
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Publication number: 20090053764Abstract: This invention provides a protein comprising consecutive amino acids, the amino acid sequence of which is illustrated in FIG. 8 (SEQ. ID No. 14) or, a fragment thereof having at least 15 amino acids, or a variant thereof, the sequence of which has at least 70% identity with the amino acid sequence of FIG. 8 (SEQ. ID No. 14) over a length of at least 400 amino acids. This invention further provides a peptide comprising a fragment of salutaridinol 7-O-acetyltransferase protein of at least 6 consecutive amino acids which is not present in other plant acetyltransferases as illustrated in FIG. 2 (SEQ. IDs No. 8 to 12). This invention further provides a nucleic acid molecule comprising consecutive nucleotides (i) the nucleic acid sequence of which is illustrated in FIG. 9 (SEQ. ID No. 13) or FIG. 10 (SEQ. ID No. 15), or (ii) a fragment thereof having a length of at least 45 nucleotides, or (iii) a variant thereof, the sequence of which has at least 70% identity with the sequence of FIG. 9 (SEQ. ID No. 13) or FIG.Type: ApplicationFiled: May 15, 2008Publication date: February 26, 2009Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventors: Toni M. Kutchan, Meinhart H. Zenk, Torsten Grothe
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Publication number: 20080201800Abstract: DNA constructions that provide for production of potent antifungal proteins in transgenic plants and transformed yeast cells are described. Methods of using the DNA constructs to produce transgenic plants that inhibit growth of plant pathogenic fungi are also disclosed. The use of transformed yeast cells containing the DNA constructs to produce the antifungal proteins and methods of isolating the antifungal proteins are also described.Type: ApplicationFiled: December 20, 2007Publication date: August 21, 2008Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventors: Dilip Maganlal Shah, Anita Kay Snyder
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Publication number: 20080196124Abstract: Methods for obtaining plants with decreased responses to auxins by reducing exprssion of endogenous MYB77 genes in plants are disclosed. Also disclosed are methods of using plant MYB77 transcriptional promoter sequences to drive expression of heterologous genes in select plant cells at select times in plant development. Methods of obtaining plants with decreased lateral root formation when grown under nutrient deficient conditions by reducing expression of endogenous MYB77 and transgenic plants with reduced expression of endogenous MYB77 genes in are also provided.Type: ApplicationFiled: April 27, 2007Publication date: August 14, 2008Applicant: DONALD DANFORTH PLANT SCIENCE CENTERInventors: Daniel P. Schachtman, Ryoung Shin