Abstract: Disclosed is a hand-held, medical, multi-channel biological information acquisition mobile terminal system, comprising two signal sensing gloves RL with a cable end embedded therein, for use in acquiring a variety of biological signals comprising multi-channel interconnected ECG, heart sounds, finger blood volume pulse, and skin impedance etc., the signal sensing gloves RL also comprising a signal acquisition device S, a signal transmission device C connected to the signal acquisition device S, and a mobile terminal T connected wirelessly or with a wired connection. The system has the characteristics of low power consumption, small size, low cost and fewer control channels needed for multi-channel connection; and the system can achieve on-site acquisition of a variety of biological information and the mobile function of electronic health records.