Abstract: The present invention relates to a Krueppel-like factor 10 (KLF10) gene expression inhibitor promoting cartilage differentiation, and more specifically, to: a composition for promoting chondrocyte differentiation or treating cartilage diseases, containing a KLF10 gene expression inhibitor promoting cartilage differentiation and inhibiting the hypertrophy and dedifferentiation of chondrocytes; a cell therapeutic agent containing the composition; a method for promoting cartilage differentiation in bone marrow stem cells, comprising a step of expressing the composition in bone marrow stem cells; and a method for screening a chondrocyte differentiation promoter or a chondrocyte therapeutic agent.
Type:
Application
Filed:
December 30, 2014
Publication date:
January 19, 2017
Applicant:
DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION F OUNDATION
Abstract: Provided is a method for preventing or treating hepatitis C by administrating a composition including, as an active ingredient, a Vitidis Vinferae Radix extract or a fraction thereof and, more specifically, to a Vitidis Vinferae Radix extract which is extracted with water and alcohol or a mixed solvent thereof, or a fraction thereof, which have remarkably low hepatotoxicity and exhibit an excellent effect of selectively inhibiting genome replication of a hepatitis C virus, and thus can be useful for preventing or treating hepatitis C.
Type:
Application
Filed:
April 29, 2014
Publication date:
April 14, 2016
Applicants:
DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION F OUNDATION, CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
Abstract: Disclosed is a nanorod semiconductor device having a contact structure, and a method for manufacturing the same. The nanorod semiconductor device having a contact structure according to one embodiment of the present disclosure includes: a transparent wafer; a transparent electrode layer formed on the transparent wafer; a nanorod layer including a plurality of semiconductor nanorods doped with dopants having a first polarity and grown on the transparent electrode layer; and a single crystal semiconductor layer doped with dopants having a second polarity and forming a certain physical contact with the ends of the semiconductor nanorods.
Type:
Application
Filed:
December 21, 2010
Publication date:
December 20, 2012
Applicant:
Dongguk University Industry-Academic Cooperation F
Inventors:
Sang Wuk Lee, Tae Won Kang, Gennady Panin, Hak Dong Cho