Abstract: The present disclosure relates to iminosugar derivatives and processes for the preparation thereof. The disclosed compounds have glycosidase inhibiting properties, and are useful in the treatment of various diseases, such as type 2 diabetes, neurodegenerative diseases or lysosomal storage disorders. The present disclosure also relates to pharmaceutical compositions containing the disclosed compounds and to their use as biochemical tools.
Type:
Application
Filed:
July 19, 2012
Publication date:
October 2, 2014
Applicants:
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), DORPHAN S.A., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Matthieu Sollogoub, Yves Bleriot, Giuseppe Prencipe, Nicolas Auberger