Abstract: The invention relates to cosmetic agents which contain, besides the usual basic cosmetic substances, natural yeast cell contents. The yeast cell contents are obtained by mechanically breaking open the yeast cell walls and by separating off the cell walls and any cell membranes, employing protective conditions. The invention relates also to extracts of yeast cell contents which contain an enriched fraction of yeast cell nuclei and which, when used in cosmetic agents, have an especially good skin-care effect. The native yeast cell contents comprise the cell contents without the cell walls, or the cell contents without cell walls and without nuclear membranes.