Patents Assigned to Dr. Franz Koehler Chemie GmbH
  • Patent number: 9603354
    Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: March 28, 2017
    Assignee: DR. FRANZ KOEHLER CHEMIE GMBH
    Inventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns
  • Patent number: 8846662
    Abstract: The invention relates to a pharmaceutical composition characterized in that it comprises a benzodiazapine and/or benzodiazapine derivative, and a non-ionic solubilizer, and induces in said combination an analogous effect to an opiate, described as a Straub phenomenon.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: September 30, 2014
    Assignee: Dr. Franz Koehler Chemie GmbH
    Inventor: Rainer Hoernecke
  • Patent number: 7977383
    Abstract: Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: July 12, 2011
    Assignee: Dr. Franz Koehler Chemie GmbH
    Inventors: Herbert de Groot, Ursula Rauen, Gernot Koehler, Wilfried Bruns