Abstract: The ethyl ester of derivatives of benzoyl ecgonine are provided having a linking group at the para position of the benzoyl group. The derivatives are used to bond to immunogenic polypeptides for production of antisera and monoclonal antibodies. The antisera and antibodies find use in assays, for treatment of cocaine overdose and detoxification.
Type:
Grant
Filed:
January 4, 2000
Date of Patent:
April 1, 2003
Assignee:
DrugAbuse Sciences, Inc.
Inventors:
Jean-Michel Scherrmann, Philippe Pouletty, Herve Galons
Abstract: The ethyl ester of derivatives of benzoyl ecgonine are provided having a linking group at the para position of the benzoyl group. The derivatives are used to bond to immunogenic polypeptides for production of antisera and monoclonal antibodies. The antisera and antibodies find use in assays, for treatment of cocaine overdose and detoxification.
Type:
Grant
Filed:
August 25, 1998
Date of Patent:
September 5, 2000
Assignee:
DrugAbuse Sciences, Inc.
Inventors:
Jean-Michel Scherrmann, Philippe Pouletty, Herve Galons