Abstract: An apparatus includes a handle, a cartridge configured to removably couple to the handle, an actuator movably coupled to the handle, and a lock operably coupled to the actuator. A first needle assembly and a second needle assembly of the cartridge are operably coupled to a first coupling portion and a second coupling portion, respectively, of the actuator when the cartridge is coupled to the handle. The first coupling portion is configured to transition the first needle assembly from a first configuration to a second configuration such that a first capture portion engages a first needle. The second coupling portion is configured to transition the second needle assembly from a first configuration to a second configuration such that a second capture portion engages the second needle. The lock is configured to selectively limit movement of the first coupling portion and the second coupling portion.

Abstract: A suturing device includes a needle, a suture, an elongate body, an actuator and a needle holder. The suture connects with the needle. The needle holder extends away from a distal end portion or is provided as part of the distal end portion of the elongate body. The needle holder includes a distal end section having a distal-most tip, and defines a needle passage for holding the needle and a distal opening. At least a portion of the suture extends through the distal opening when the needle is received in the needle passage and the actuator is in a first operating position. At least a portion of the suture extends along the needle passage toward the distal opening between the needle and an inner surface of the needle holder when the needle is received in the needle passage and the actuator is in the first operating position.