Patents Assigned to Duska Scientific Co.
  • Methods of Diagnosing, Monitoring and Treating Pulmonary Diseases
    Publication number: 20100286274
    Abstract: The invention includes methods of discriminating asthma from obstructive pulmonary disease, of treating pulmonary diseases, of treating cough, of assessing the efficacy of a treatment for an obstructive pulmonary disease, and of inhibiting activation of a P2-purinoreceptor (P2R).
    Type: Application
    Filed: July 19, 2010
    Publication date: November 11, 2010
    Applicant: DUSKA SCIENTIFIC CO.
    Inventors: Amir Pelleg, Peter J. Barnes, Sergei A. Kharitonov
  • Formulations of ATP and Analogs of ATP
    Publication number: 20100222294
    Abstract: This disclosure provides solutions and compositions (e.g., pharmaceutical solutions and compositions) containing adenosine 5?-triphosphate (ATP) or an analog thereof. In addition, it features methods of making and using the solutions and compositions.
    Type: Application
    Filed: March 1, 2010
    Publication date: September 2, 2010
    Applicant: DUSKA SCIENTIFIC CO.
    Inventor: Amir Pelleg
  • INHIBITION OF NEURONAL DAMAGE
    Publication number: 20100074884
    Abstract: Materials and Methods for inhibiting neuronal damage are provided herein. In particular, materials and methods for inhibiting neuronal damage associated with pathological action of extracellular ATP are provided herein.
    Type: Application
    Filed: May 31, 2006
    Publication date: March 25, 2010
    Applicant: DUSKA SCIENTIFIC CO.
    Inventors: Francesco Divirgilio, Valentina Resta, Lucia Galli
  • Screening method for modulation of human mast cell activation
    Patent number: 6465441
    Abstract: Human mast cell activation is modulated by ATP binding to P2-purinoceptors on the mast cell surface. ATP binding to the purinoceptors provides a target for therapeutic intervention for the treatment of disorders characterized by undesireable mast cell mediator release, such as asthma and allergy. Inhibitors of ATP binding to mast cell P2-purinoceptors are useful therapeutic agents for treatments of those disorders. Methods of treatment using agents, and in vitro screening assays for selection of the therapeutic agents, are described.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: October 15, 2002
    Assignee: Duska Scientific Co.
    Inventors: Amir Pelleg, Edward S. Schulman
  • Modulation of human mast cell activation
    Patent number: 6372724
    Abstract: Human mast cell activation is modulated by ATP binding to P2-purinoceptors on the mast cell surface. ATP binding to the purinoceptors provides a target for therapeutic intervention for the treatment of disorders characterized by undesirable mast cell mediator release, such as asthma and allergy. Inhibitors of ATP binding to mast cell P2-purinoceptors are useful therapeutic agents for treatment of those disorders. Methods of treatment using such agents, and in vitro screening assays for selection of the therapeutic agents, are described.
    Type: Grant
    Filed: December 2, 1999
    Date of Patent: April 16, 2002
    Assignee: Duska Scientific Co.
    Inventors: Amir Pelleg, Edward S. Schulman