Patents Assigned to East Grinstead Medical Research Trust
  • Repair of nerve damage
    Patent number: 6821946
    Abstract: The invention provides a method of treating nerve damage involving administering to the damaged nerve an effective non-toxic amount of an MGF (mechano-growth factor) Insulin-like Growth Factor I (IGF-I) isoform which includes amino acid sequences encoded by nucleic acid sequences of IGF-I exons 4, 5 and 6 in the reading frame of MGF and having the ability to reduce motoneurone loss by 20% or greater in response to nerve avulsion.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: November 23, 2004
    Assignees: University College London, East Grinstead Medical Research Trust
    Inventors: Geoffrey Goldspink, Giorgio Terenghi