Abstract: The invention relates to an isolated polynucleotide sequence from the genome of Bacillus stearothermophilus (Geobacillus stearothermophilus) and an amino acid sequence encoded by the polynucleotide sequence, the corresponding amino acid sequence comprising a novel enzyme, Tirt (thermostable intron reverse transcriptase), having reverse transcriptase activity and retaining that activity at temperatures of up to about 75° C.
Type:
Grant
Filed:
March 10, 2004
Date of Patent:
March 2, 2010
Assignee:
East Tennessee State Univ. Research Foundation