Patents Assigned to Ecole polytechnique fédérale de Lausanne (EPFL)
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Patent number: 11594694Abstract: The invention relates to an optoelectronic and/or photoelectrochemical device including a conductive support layer, n-type semiconductor, a sensitizer or light-absorber layer, a hole transporting layer, a spacer layer and a back contact, wherein the n-type semiconductor is in contact with the sensitizer or light-absorber layer, the sensitizer or light-absorber layer includes a perovskite or metal halide perovskite material, the hole transporting layer is in direct contact with the sensitizer or light-absorber layer and includes an inorganic hole transporting material or inorganic p-type semiconductor, the spacer layer is between the hole transporting layer and the back contact and includes a material being different from the inorganic hole transporting material and the material of the back contact.Type: GrantFiled: May 3, 2018Date of Patent: February 28, 2023Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)Inventors: Neha Arora, Mohammad Ibrahim Dar, Shaik Mohammed Zakeeruddin, Michael Graetzel
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Patent number: 11583860Abstract: A device for aggregating cells includes a cavity. The cavity includes a plurality of microwells for receiving at least one cell. Each of the microwells includes a vertical sidewall and a curved bottom. The microwells are made in a hydrogel layer. Each of said microwells has a diameter and an interwell distance between one microwell and another microwell, wherein a ratio for the interwell distance to the diameter is less than or equal to 1/10.Type: GrantFiled: December 22, 2014Date of Patent: February 21, 2023Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)Inventors: Sylke Höhnel, Nathalie Brandenberg, Matthias Lutolf
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Patent number: 11579523Abstract: A method for manufacturing glass-based micro- and nanostructure comprising the step of dewetting a thin-film glass layer on a textured substrate to form the micro- and nanostructure from the thin-film glass layer.Type: GrantFiled: February 7, 2020Date of Patent: February 14, 2023Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Fabien Sorin, Louis Martin-Monier, Alexis Page, Tapajyoti Dasgupta
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Patent number: 11577005Abstract: The composition for bone regeneration, comprises a) a first phase (3) comprising a plurality of cross-linked hydrogel chunks (1) having a mean diameter of less than 1000 ?m and incorporating an amount of mineral particles (2); and b) a second phase (4) comprising a physiologically-compatible aqueous liquid acting as a carrier for the chunks; the chunks being embedded in the second phase (4). The mineral particles (2) have a mean diameter of less than 10 ?m and the amount of the mineral particles (2) is less than 20 weight-% of the first phase.Type: GrantFiled: September 14, 2015Date of Patent: February 14, 2023Assignee: ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL)Inventors: Ulrike Kettenberger, Dominique Pioletti
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Patent number: 11542371Abstract: The present invention relates to functionalized hydrogel networks grafted with at least one moiety for use in numerous fields, from cosmetics to surgery and medicine.Type: GrantFiled: September 14, 2017Date of Patent: January 3, 2023Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Sandrine Gerber, Solene Passemard, Christine Wandrey, Leo Buhler, Philippe Morel
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Publication number: 20220399127Abstract: A data processing apparatus locates source cells responsible for an electrical anomaly in a subject's body part. The apparatus comprises means for: obtaining one or more electrical signals resulting from electrical activity of one or more source cells in the subject's body part; time-reversing the one or more electrical signals for obtaining one or more time-reversed electrical signals; feeding the one or more time-reversed electrical signals into a simulation model of the subject's body part, which is configured to model anatomy and/or electrical activity of the subject's body part, to cause the time-reversed electrical signals when fed into the simulation model to converge in the simulation model at one or more convergence locations; and identifying the one or more convergence locations in the simulation model thereby allowing locating the source cells responsible for the electrical anomaly.Type: ApplicationFiled: November 19, 2019Publication date: December 15, 2022Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Esfandiar SOROUCHYARI, Farhad RACHIDI-HAERI, Ali DADRAS
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Patent number: 11524092Abstract: The particle (1) is suitable for the manufacture of an implantable soft tissue engineering material and comprises: a three-dimensionally warped and branched sheet (2) where (i) the three-dimensionally warped and branched sheet (2) is made from a biocompatible material having a Young's modulus of 1 kPa to 1 GPa; (ii) the three-dimensionally warped and branched sheet (2) has an irregular shape which is encompassed in a virtual three-dimensional envelope (3) having a volume VE; (iii) the three-dimensionally warped and branched sheet (2) has a mean sheet thickness T; iv) the three-dimensionally warped and branched sheet (2) has a volume VS; (v) the particle (1) has a Young's modulus of 100 Pa to 15 kPa; and (vi) the particle (1) further comprises a number of protrusions where the three-dimensionally warped and branched sheet (2) reaches the envelope (3); (vii) the particle (1) has a number of interconnected channel-type conduits (5) defined by the branching of the sheet (2) and/or by voids in the sheet (2); and (Type: GrantFiled: October 4, 2018Date of Patent: December 13, 2022Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)Inventors: Amélie Béduer, Thomas Braschler, Philippe Renaud
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Patent number: 11513419Abstract: A light pulse source and method for generating repetitive optical pulses are described. The light pulse source includes a continuous wave cw laser device, an optical waveguide optically coupled with the laser device, an optical microresonator, and a tuning device. The optical microresonator coupling cw laser light via the waveguide into the microresonator, which, may include, a light field in a soliton state with soliton shaped pulses coupled out of the microresonator for providing the repetitive optical pulses. The laser device includes a chip based semiconductor laser, the microresonator and/or the waveguide may reflect an optical feedback portion of light back to the semiconductor laser, which may provide self-injection locking relative to a resonance frequency of the microresonator. The tuning device is arranged for tuning at least one of a driving current and a temperature of the semiconductor laser such that the microresonator may provide the soliton state.Type: GrantFiled: September 17, 2018Date of Patent: November 29, 2022Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)Inventors: Tobias Kippenberg, Michael L. Gorodetsky, Arslan Sajid Raja, Hairun Guo
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Patent number: 11511116Abstract: The present invention relates to systems and methods for planning and/or providing neuromodulation. An example system includes a first data input module for stimulation related basic data, a second data input module for stimulation related response data, a transfer module configured and arranged such that the stimulation related basic data received by the data input module are linked and/or translated into and/or with the response data and/or artificial response data created by the transfer module, wherein the data generated by the transfer module are transfer data, the transfer data comprising link data and/or translation data and/or artificial response data, and a mapping module configured and arranged such that based on the stimulation related basic data and stimulation related response data and the transfer data a digital characteristic map is generated, which describes an interrelation between the stimulation related basic data and the stimulation related response data and the transfer data.Type: GrantFiled: November 29, 2018Date of Patent: November 29, 2022Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), ONWARD Medical N.V.Inventors: Fabien Wagner, Karen Minassian, Marco Capogrosso, Gregoire Courtine, Robin Brouns, Jurriaan Bakker, Andre Kleibeuker, Bert Bakker, Vincent Delattre
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Patent number: 11497445Abstract: Sensor system comprising a frame supporting a force-sensing tip arranged to generate a signal based upon a force applied by said force-sensing tip to a material to be tested, the system further comprising: an input drum mounted in said frame such that it can rotate about an input axis of rotation; an output lever supported by said frame by means of an output revolute joint defining an output axis of rotation; wherein said force-sensing tip is mounted on said output lever such that said force-sensing tip is arranged to be brought into contact with a material to be tested; and wherein said sensor system comprises a mechanical transmission arranged to kinematically link said input drum to said output lever such that a rotation of said input drum about said input axis of rotation causes said output lever to pivot in an oscillatory manner about said output axis of rotation.Type: GrantFiled: February 27, 2020Date of Patent: November 15, 2022Assignee: ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL)Inventors: Simon Henein, Charles Baur, Thomas Fussinger, Hubert Schneegans, Lisa Bonnefoy
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Patent number: 11476357Abstract: The present invention relates to a Semiconductor device including a first electrode, a second electrode and at least one semiconductor material or layer between the first and second electrode. The semiconductor device further includes at least one field plate structure for increasing a breakdown voltage of the semiconductor device. The at least one field plate structure comprises at least two recesses in the at least one semiconductor material or layer, the at least two recesses defining a semiconductor region therebetween, and a third electrode contacting or provided on the semiconductor region.Type: GrantFiled: September 28, 2017Date of Patent: October 18, 2022Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Elison de Nazareth Matioli, Jun Ma
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Patent number: 11473087Abstract: The present invention provides compositions and methods for down-modulating the expression and/or the immuno-suppressive activity of i) the FMRP protein, ii) an mRNA encoding the FMRP protein, and/or iii) the FMR1 gene for the treatment and/or prevention of primary cancer and/or cancer metastasis in a subject in need thereof.Type: GrantFiled: May 6, 2020Date of Patent: October 18, 2022Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Qiqun Zeng, Douglas Hanahan
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Publication number: 20220327048Abstract: Data transformer apparatus comprising at least a dispatcher module (D), a reader module (R), a converter module (C) and a writer module (W). The dispatcher module (D) is configured to: receive a data transformation request (DTR) including: a first information item (X1) associated to a memory address where data to be transformed (Data1) are stored and to a type attribute (T) of said data to be transformed (Data1); a second information item (X2) indicating a memory address where transformed data (Data2), obtained from said data to be transformed (Data1), have to be written. The reader module (R) is configured to: retrieve the data to be transformed, according to said first information item (X1); obtain the type attribute (T) of the data to be transformed (Data1), based on said first information item (X1); send the data to be transformed (Data1) and the type attribute (T) thereof to the converter module (C).Type: ApplicationFiled: August 27, 2019Publication date: October 13, 2022Applicant: Ecole Polytechnique Federale de Lausanne (EPFL)Inventors: Arash POURHABIBI ZARANDI, Siddharth GUPTA, Hussein KASSIR, Mark SUTHERLAND, Zilu TIAN, Mario Paulo DRUMOND LAGES DE OLIVEIRA, Babak FALSAFI, Christoph KOCH
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Patent number: 11467123Abstract: A biosensor includes a source element; a drain element; a semiconductor channel element between the source element and the drain element for forming an electrically conductive channel with adjustable conductivity between the source and drain elements; a first gate element configured to be electrically biased to set a given operational regime of the sensor with given electrical conductivity of the channel; and a second gate element, physically separate from the first gate element, configured to contact a solution comprising analytes allowed to interact with a gate contact surface of the second gate element to generate a surface potential change dependent on the concentration of the analytes in the solution. The channel element is substantially fully depleted allowing the first and second gate elements to be electrostatically coupled such that the surface potential change at the second gate element is configured to modify the electrical conductivity of the channel.Type: GrantFiled: September 8, 2017Date of Patent: October 11, 2022Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Mihai Adrian Ionescu, Hoël Guerin
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Patent number: 11459234Abstract: The present relates to a carbon material having a 3D structure and made of graphene oxide and carbon nanotubes, characterized in that the 3D structure consists in that the carbon nanotubes are located with some agglomeration between the graphene oxide layers so as to extend the spacing between the graphene oxide layers.Type: GrantFiled: January 14, 2019Date of Patent: October 4, 2022Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Heena Yang, Andreas Züttel
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Patent number: 11458067Abstract: A fully wearable system used for communication and information transfer between two users or between a user and a machine to render an effective and intuitive physical interface for combined input and output functions, the fully wearable system including a bidirectional wearable skin including distributed actuator and sensing elements, the actuator and sensing elements including a multimodal actuation layer and a sensing layer, the bidirectional wearable skin being flexible and stretchable, and a portable control device for controlling the distributed actuator and sensing elements, and reading signals from the sensing layer, the portable control device is configured to perform pixilated actuation for both micro- and macrostimulation of a body of a wearer by an actuation frequency and stimulation amplitude.Type: GrantFiled: June 1, 2018Date of Patent: October 4, 2022Assignee: ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL)Inventors: Harshal Arun Sonar, Matthew Aaron Robertson, Sagar Dattatray Joshi, Tigmanshu Bhatnagar, Jamie Paik
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Publication number: 20220307878Abstract: The present invention concerns an elongated capacitive sensor for fluid monitoring. The sensor comprising: a fibre support made of a dielectric material or dielectric composite material; and a first electrode and a second electrode arranged longitudinally along the fibre support, the first and second electrodes forming together with the fibre support a capacitive sensing element whose capacitance is dependent upon one or more electrical properties of one or more materials inside the support and/or outside the support, and/or is dependent upon a change of materials configuration and associated overall change of one or more electrical properties inside the support and/or outside the support.Type: ApplicationFiled: August 26, 2020Publication date: September 29, 2022Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Fabien SORIN, William ESPOSITO, Véronique MICHAUD, Chaoqun DONG, Baris ÇAGLAR, Dang Tung NGUYEN
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Patent number: 11446861Abstract: A method for producing a three-dimensional object comprising computing a sequence of back-projections describing the three-dimensional object to be formed from different orientation angles of the object, defining a sequence of patterns of light using the back-projections, and irradiating with each of the patterns of light at the respective corresponding orientation angle. According to the defined sequence, a photoresponsive material is capable of altering its material phase, upon irradiation by light, thereby creating a three-dimensional distribution of alterations within the photoresponsive medium which physically reproduces the three-dimensional object, thereby creating the three-dimensional object.Type: GrantFiled: August 23, 2018Date of Patent: September 20, 2022Assignee: Ecole PolyTechnique Federale de Lausanne (EPFL)Inventors: Damien Loterie, Paul Delrot, Christophe Moser
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Publication number: 20220287640Abstract: Systems and methods are provided for that use noninvasively measured physiologic parameters to predict in real time noninvasively unobservable cardiovascular parameters by employing a one-dimensional arterial tree numerical model calibrated with representative patient data. The numerical model further may be trained and calibrated on a larger database that includes synthetic data using machine-learning algorithms to provide a robust generalized estimator for multiple cardiovascular and hemodynamic parameters.Type: ApplicationFiled: August 14, 2020Publication date: September 15, 2022Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Vasiliki BIKIA, Stamatia PAGOULATOU, Nikolaos STERGIOPULOS
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Patent number: 11440796Abstract: The present relates to a Metal hydride compressor control method for generating a variable output pressure P_desired_outPut, comprising a first step of inflowing gaseous hydrogen into a metal hydride compartment at a constant temperature and then stopping the gaseous hydrogen inflow, a second step of heating the metal hydride to a predetermined temperature which corresponds to a temperature which passes through the ?+? phase at the desired output pressure P_desired_output, a third step of opening the output connection of the compressor and keeping it at a constant pressure by regulating the temperature to keep a constant output pressure P_desired_outPut until the system completely leaves the ?+? phase.Type: GrantFiled: November 16, 2018Date of Patent: September 13, 2022Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Noris Gallandat, Andreas Züttel