Patents Assigned to Edico Genome Corporation
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Patent number: 11842796Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the integrated circuit that may be connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits may be arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the bioinformatics analysis on the reads of genomic data. Each subset of the hardwired digital logic circuits may be formed in a wired configuration to perform the one or more steps in the bioinformatics analysis.Type: GrantFiled: March 27, 2020Date of Patent: December 12, 2023Assignee: Edico Genome CorporationInventors: Pieter van Rooyen, Michael Ruehle, Rami Mehio
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Bioinformatics systems, apparatus, and methods executed on an integrated circuit processing platform
Patent number: 11043285Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the integrated circuit connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.Type: GrantFiled: February 20, 2018Date of Patent: June 22, 2021Assignee: Edico Genome CorporationInventors: Pieter Van Rooyen, Robert McMillen, Michael Ruehle -
Patent number: 10622096Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the integrated circuit that may be connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits may be arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the bioinformatics analysis on the reads of genomic data. Each subset of the hardwired digital logic circuits may be formed in a wired configuration to perform the one or more steps in the bioinformatics analysis.Type: GrantFiled: September 8, 2017Date of Patent: April 14, 2020Assignee: Edico Genome CorporationInventors: Pieter van Rooyen, Michael Ruehle, Rami Mehio
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Patent number: 10216898Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.Type: GrantFiled: February 17, 2017Date of Patent: February 26, 2019Assignee: Edico Genome CorporationInventors: Robert J. McMillen, Pieter van Rooyen, Michael Ruehle
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Patent number: 10210308Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.Type: GrantFiled: April 23, 2018Date of Patent: February 19, 2019Assignee: Edico Genome CorporationInventors: Pieter van Rooyen, Michael Ruehle, Robert J. McMillen
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Patent number: 10068052Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data is provided. Particularly, a genomics analysis platform for executing a sequence analysis pipeline is provided. The genomics analysis platform includes one or more of a first integrated circuit, where each first integrated circuit forms a central processing unit (CPU) that is responsive to one or more software algorithms that are configured to instruct the CPU to perform a first set of genomic processing steps of the sequence analysis pipeline.Type: GrantFiled: February 27, 2018Date of Patent: September 4, 2018Assignee: Edico Genome CorporationInventors: Pieter van Rooyen, Michael Ruehle, Rami Mehio, Gavin Stone, Mark David Hahm, Eric Ojard, Amnon Ptashek
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Patent number: 9940266Abstract: A method and system for correlating genome data with EMR/PHR data is disclosed herein. The method includes identifying a plurality of sources of genome data. The method also includes generating an index file for each of the plurality of genome files. The method also includes transmitting each index file to a central depository. The method also includes identifying electronic medical record (EMR) and/or personal health record (PHR) data at each source of the plurality of sources of genome data. The method also includes correlating each genome file of the plurality of genome files with a corresponding EMR/PHR data.Type: GrantFiled: March 21, 2016Date of Patent: April 10, 2018Assignee: Edico Genome CorporationInventors: Pieter Van Rooyen, Gavin Stone, Lucian Iancovici
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Patent number: 9697327Abstract: A “dynamic” reference is presented that utilizes population level information to improve reference-based alignment to detect novel, deleterious, or functional variants in clinical sequencing applications. An automatically updated database of known genetic variants is provided to a memory connected with an integrated circuit configured for genetic sequence data with the dynamic reference and reference variants.Type: GrantFiled: February 24, 2015Date of Patent: July 4, 2017Assignee: Edico Genome CorporationInventors: Robert McMillen, Michael Ruehle, John Cooper Roddey
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Patent number: 9576103Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.Type: GrantFiled: April 23, 2015Date of Patent: February 21, 2017Assignee: EDICO GENOME CORPORATIONInventors: Robert J. McMillen, Pieter Van Rooyen, Michael Ruehle
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Patent number: 9342652Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.Type: GrantFiled: November 22, 2015Date of Patent: May 17, 2016Assignee: Edico Genome CorporationInventors: Pieter Van Rooyen, Robert J. McMillen, Michael Ruehle
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Patent number: 9235680Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.Type: GrantFiled: May 21, 2014Date of Patent: January 12, 2016Assignee: Edico Genome CorporationInventors: Pieter Van Rooyen, Robert J. McMillen, Michael Ruehle