Abstract: The present invention relates to multi-phase compositions for treating vaginal infections, for example, infections caused by Trichomonas vaginitis. The compositions, which are preferably formulated as a cream or pessary, comprise a continuous phase containing anti-vaginitis medicament for rapid, initial release and porous particles adapted for the delayed release of anti-vaginitis medicaments. Metronidazole is the preferred anti-trichomal medicament.
Type:
Grant
Filed:
June 24, 1996
Date of Patent:
November 16, 1999
Assignee:
EDKO Trading and Representation Company Limited
Abstract: The invention provides a multiphase pharmaceutical composition for combatting an anorectal disease comprising at least one phase containing one or more medicaments for combatting said disease and at least one phase adapted for delayed release of a silicone oil whereby application of said composition at a region affected by said disease deposits said medicament or medicaments thereon and a layer of silicone oil is formed thereover, so protecting the medicaments from erosion by aqueous media.
Type:
Grant
Filed:
August 28, 1991
Date of Patent:
May 9, 1995
Assignee:
EDKO Trading and Representation Company Limited