Patents Assigned to Efamol Holding PLC
  • Patent number: 5614208
    Abstract: Atopic eczema, breast pain or premenstrual syndrome are treated by administering to a person in need of same a composition containing at least 20% di-linoleoyl-mono-gamma-linolenyl glycerol by weight.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: March 25, 1997
    Assignee: Efamol Holdings PLC
    Inventors: David F. Horrobin, Yung-Sheng Huang
  • Patent number: 5580556
    Abstract: The use of one or more of gamma-linolenic acid, dihomo-gamma-linolenic acid and arachidonic acid for the manufacture of a medicament for use in enhancement of the anti-viral, anti-cancer or anti-inflammatory effects of interferons; the medicament containing or being for use with a medicament containing one or more interferons when not solely for enhancement of the effect of endogenous interferons.
    Type: Grant
    Filed: January 3, 1995
    Date of Patent: December 3, 1996
    Assignee: Efamol Holdings PLC
    Inventor: David F. Horrobin
  • Patent number: 5552150
    Abstract: A natural or synthetic glycerol oil which comprises at least 20% by weight, preferably at least 25% of di-linoleoyl-mono-gamma-linolenyl-glycerol (DLMG), is used to supplement foods, nutritional compositions and in skin and hair care compositions.
    Type: Grant
    Filed: November 30, 1993
    Date of Patent: September 3, 1996
    Assignee: Efamol Holdings PLC
    Inventors: David F. Horrobin, Yung-Sheng Huang
  • Patent number: 5422115
    Abstract: Methods of treatment of the human or animal body are provided to combat conditions responsive to lithium and/or C.sub.18-22 polyunsaturated fatty acid therapy, including conditions associated with essential lithium deficiency, and also transfer of lipid-enveloped viruses between humans or animals or between cells within a human or animal body. The methods include administration of an effective amount of a lithium salt of a C.sub.18-22 polyunsaturated fatty acid. Devices for combatting transmission of viral diseases including lithium salts of a C.sub.18-22 polyunsaturated fatty acid are also provided.
    Type: Grant
    Filed: October 20, 1992
    Date of Patent: June 6, 1995
    Assignee: Efamol Holding PLC
    Inventor: David F. Horrobin
  • Patent number: 5328691
    Abstract: A natural or synthetic glycerol oil which comprises at least 20% by weight, preferably at least 25% of di-linoleoyl-mono-gamma-linolenyl-glycerol (DLMG), is used to supplement foods, nutritional compositions and in skin and hair care compositions.
    Type: Grant
    Filed: June 1, 1992
    Date of Patent: July 12, 1994
    Assignee: Efamol Holdings PLC
    Inventors: David F. Horrobin, Yung-Sheng Huang
  • Patent number: 5318991
    Abstract: Reduction of urinary calcium excretion in humans or animals by the administration of GLA or DGLA as much or in salt or other pharmacologically acceptable form, optionally in association with EPA, DHA or other EFA in similar forms, is also useful in the treatment of nephrocalcinosis, renal stones and osteoporosis.
    Type: Grant
    Filed: April 22, 1993
    Date of Patent: June 7, 1994
    Assignee: Efamol Holdings PLC
    Inventors: David F. Horrobin, Alfred C. Buck
  • Patent number: 5276020
    Abstract: Anti-virals wherein a linoleyl, gamma-linolenyl or other unsaturated long chain fatty acyl group is borne directly on a hydroxy or amino group of the sugar/sugar analogue or heterocyclic moiety of a nucleoside or nucleoside analogue.
    Type: Grant
    Filed: December 14, 1992
    Date of Patent: January 4, 1994
    Assignee: Efamol Holdings plc
    Inventors: David F. Horrobin, John C. M. Stewart, Michael D. Winther
  • Patent number: 5223271
    Abstract: The present invention provides a method of treatment and/or prophylaxis of the human or animal body to combat Molluscum Contagiosum, said treatment comprising topically administering a therapeutically or prophylactically effective amount of a physiologically acceptable lithium compound to affected areas on said body.It also extends to pharmaceutical compositions comprising a physiologically acceptable lithium compound together with at least one keratolytic and/or skin penetration assisting agent and at least one pharmaceutically acceptable carrier or excipient.
    Type: Grant
    Filed: September 24, 1991
    Date of Patent: June 29, 1993
    Assignee: Efamol Holdings PLC
    Inventor: David F. Horrobin
  • Patent number: 5216142
    Abstract: Anti-virals wherein a linoleyl, gamma-linolenyl or other unsaturated long chain fatty acyl group is borne directly on a hydroxy or amino group of the sugar/sugar analogue or heterocyclic moiety of a nucleoside or nucleoside analogue.
    Type: Grant
    Filed: April 10, 1990
    Date of Patent: June 1, 1993
    Assignee: Efamol Holdings plc
    Inventors: David F. Horrobin, John C. M. Stewart, Michael D. Winther
  • Patent number: 5198468
    Abstract: Treatment or prevention of memory loss with a medicament consisting of an n-6 essential fatty acid selected from GLA, DGLA, AA, adrenic acid and the 22:5 n-6 acid and an n-3 essential fatty acid selected from the 18:4 n-3 and 20:4 n-3 acids, EPA, the 22:5 n-3 acid and DHA.
    Type: Grant
    Filed: June 19, 1991
    Date of Patent: March 30, 1993
    Assignee: Efamol Holdings Plc
    Inventor: David F. Horrobin
  • Patent number: 5178873
    Abstract: A method of inhibiting phospholipase A2 in the control of inflammation, wherein delta-6,9,12,15-octadecatetraenoic acid (stearidonic acid) and/or delta-8,11,14,17-eicosatetraenoic acid is administered alone or in a pharmaceutically acceptable diluent or carrier.
    Type: Grant
    Filed: May 23, 1991
    Date of Patent: January 12, 1993
    Assignee: Efamol Holdings PLC
    Inventors: David F. Horrobin, Michael J. Finnen
  • Patent number: 5162519
    Abstract: This invention provides novel compounds for therapy of tumors susceptible to necrosis when an appropriate compound is administered followed by illumination with light of a wavelength absorbed by the compound, the compounds being dihydro porphyrins of the formula, or the corresponding tetra-hydro porphyrins: ##STR1## where n=1 to 3 and each substituent R, the same or different and at the same or different position in its respective substituent phenyl ring, is an hydroxy group.
    Type: Grant
    Filed: November 26, 1990
    Date of Patent: November 10, 1992
    Assignee: Efamol Holdings plc
    Inventors: Raymond Bonnett, Morris C. Berenbaum
  • Patent number: 5120760
    Abstract: Method of, and preparations of medicaments for, treating schizophrenia and/or associated tardive dyskinesia by combining an essential fatty acid selected from GLA and higher n-6 series acides with an essential fatty acid selected from stearidonic acid and higher n-3 series acids in effective daily amounts of 10 mg and 50 g of each acid.
    Type: Grant
    Filed: September 25, 1990
    Date of Patent: June 9, 1992
    Assignee: Efamol Holdings PLC
    Inventor: David F. Horrobin
  • Patent number: 5116624
    Abstract: A pharmaceutical composition of GLA or DGLA and bioavailable selenium, optionally also with an 18:4 or higher n-3 EFA and/or bioavailable zinc.
    Type: Grant
    Filed: January 9, 1991
    Date of Patent: May 26, 1992
    Assignee: Efamol Holdings PLC
    Inventors: David F. Horrobin, Frank Corrigan
  • Patent number: 5116871
    Abstract: The use of one or more of the 6-desaturated or higher EFAs of each of the n-6 and n-3 series for the manufacture of a medicament for use in the treatment of post-viral fatigue syndrome (otherwise known as myalgic encephalomyelitis (ME)).
    Type: Grant
    Filed: August 24, 1989
    Date of Patent: May 26, 1992
    Assignee: Efamol Holdings PLC
    Inventors: David F. Horrobin, John C. M. Stewart
  • Patent number: 4997657
    Abstract: A composition, particularly an oral composition, for improving the smoothness of the skin, wherein GLA or DGLA or both as such or in the form of physiologically acceptable and equivalent derivatives are brought into administrable form with a carrier or diluent.
    Type: Grant
    Filed: March 9, 1989
    Date of Patent: March 5, 1991
    Assignee: Efamol Holdings, plc
    Inventors: David F. Horrobin, John C. M. Stewart
  • Patent number: 4992257
    Abstract: This invention provides novel compounds for therapy of tumors susceptible to necrosis when an appropriate compound is administered followed by illumination with light of a wavelength absorbed by the compound, the compounds being dihydro porphyrins of the formula, or the corresponding tetra-hydro prophyrins: ##STR1## where n=1 to 3 and each substitutent R, the same or different and at the same or different position in its respective substituent phenyl ring, is an hydroxy group.
    Type: Grant
    Filed: March 2, 1989
    Date of Patent: February 12, 1991
    Assignee: Efamol Holdings PLC
    Inventors: Raymond Bonnett, Morris C. Berenbaum
  • Patent number: 4977187
    Abstract: Method of, and preparations of medicaments for, treating schizophrenia and/or associated tardive dyskinesia by combining an essential fatty acid selected from GLA and higher N-6 series acids with an essential fatty acid selected from stearidonic acid and higher n-3 series acids in effective daily amounts of 10 mg and 50 g of each acid.
    Type: Grant
    Filed: June 1, 1989
    Date of Patent: December 11, 1990
    Assignee: Efamol Holdings PLC
    Inventor: David F. Horrobin
  • Patent number: 4970076
    Abstract: Composition of a cyclosporin and GLA and DGLA or derivative thereof convertible in the body thereto alone or in a pharmaceutical diluent or carrier.
    Type: Grant
    Filed: December 6, 1988
    Date of Patent: November 13, 1990
    Assignee: Efamol Holdings PLC
    Inventor: David F. Horrobin