Abstract: A device for capturing and concentrating volatile organic compounds (VOCs) in a sample of breath air. The device includes an intake for accepting an air sample; a disposable mouth piece; a sensor array for measuring physical parameters of the air sample; an exhaled air sampler for capturing a pre-determined volume of air; a concentrator for concentrating VOCs in the air sample; and an ionic liquid collector, the latter of which may be removed from the device. The ionic liquid collector, which may have one compartment or multiple compartments, includes at least one ionic liquid. Analysis of VOCs in the ionic liquid or liquids may identify biomarkers that can provide a medical diagnosis for a human patient based on a sample of breath air.

Abstract: A device for measuring the concentrations of volatile organic compounds (VOCs) in air. The device includes a sample chamber for accepting a sample of air; at least one ionization source for ionizing VOCs in the sample; an ionic liquid trap containing an ionic liquid that captures the ionized VOCs; a circuit for generating a electric current through the device to run the ionization and capture of the ionized VOCs; and a chemical sensor for detecting and measuring concentrations of the VOCs in the sample of air. The device, which may be hand-held, portable, or designed to sit on a bench top, may be used on any animal, including humans.

Abstract: A sol-gel deposition technique that forms ion sensitive layers is compatible with CMOS fabrication methods and is applied to build sensors of concentrations of solutions of selected target ions. The ion sensitive sensor may be formed on an exposed portion of a signal trace of a printed circuit board. Additionally, the ion sensitive layer may be formed within an ion sensitive field effect transistor.

Abstract: A device for capturing and concentrating volatile organic compounds (VOCs) in a sample of breath air. The device includes an intake for accepting an air sample; a disposable mouth piece; a sensor array for measuring physical parameters of the air sample; an exhaled air sampler for capturing a pre-determined volume of air; a concentrator for concentrating VOCs in the air sample; and an ionic liquid collector, the latter of which may be removed from the device. The ionic liquid collector, which may have one compartment or multiple compartments, includes at least one ionic liquid. Analysis of VOCs in the ionic liquid or liquids may identify biomarkers that can provide a medical diagnosis for a human patient based on a sample of breath air.

Abstract: A device for measuring the concentrations of volatile organic compounds (VOCs) in air. The device includes a sample chamber for accepting a sample of air; at least one ionization source for ionizing VOCs in the sample; an ionic liquid trap containing an ionic liquid that captures the ionized VOCs; a circuit for generating a electric current through the device to run the ionization and capture of the ionized VOCs; and a chemical sensor for detecting and measuring concentrations of the VOCs in the sample of air. The device, which may be hand-held, portable, or designed to sit on a bench top, may be used on any animal, including humans.