Abstract: There is provided an inhalation device for delivering a deliverable agent in the form of an aerosol or vapour to a user. The device comprises a solid, porous carrier material having a defined porosity, and a deliverable agent located within the pores of the carrier material. The device is operable to heat the carrier material and vaporise the deliverable agent. Deliverable agents that may be delivered to the user include active pharmaceutical ingredients. Suitable materials for the porous carrier material include chemically bonded ceramic materials and geopolymeric materials.
Abstract: A transdermal drug administration device comprising a drug delivery element (10) defining a contact surface (12) for location, in use, against a patient's skin. The drug delivery element (10) includes a sustained-release pharmaceutical composition. The composition comprises a network of a carrier material having a high mechanical strength and an active pharmaceutical ingredient. The active pharmaceutical ingredient is co-formedly interspersed within pores in the solid, continuous network of the carrier material.
Type:
Grant
Filed:
April 5, 2019
Date of Patent:
August 11, 2020
Assignee:
Emplicure AB
Inventors:
Håkan Engqvist, Susanne Bredenberg, Anders Petterson, Thomas Lundqvist, Anna Dahlgren, Anders Sågström
Abstract: There is provided a sustained-release pharmaceutical composition comprising a solid, continuous network comprising an excipient with a high mechanical strength, which network also comprises pores, within which pores is interspersed a mixture of an active ingredient and a film-forming agent, characterised in that said pores are formed during the production of the composition. Compositions of the invention find particularly utility as abuse-resistant formulations comprising opioid analgesics that may be employed in the treatment of chronic pain.
Type:
Grant
Filed:
March 9, 2017
Date of Patent:
January 28, 2020
Assignee:
Emplicure AB
Inventors:
Susanne Bredenberg, Anna Dahlgren, Anders Sågström, Håkan Engqvist
Abstract: A transdermal drug administration device comprising a drug delivery element (10) defining a contact surface (12) for location, in use, against a patient's skin. The drug delivery element (10) includes a sustained-release pharmaceutical composition. The composition comprises a network of a carrier material having a high mechanical strength and an active pharmaceutical ingredient. The active pharmaceutical ingredient is co-formedly interspersed within pores in the solid, continuous network of the carrier material.
Type:
Grant
Filed:
September 5, 2011
Date of Patent:
April 9, 2019
Assignee:
EMPLICURE AB
Inventors:
Håkan Engqvist, Susanne Bredenberg, Anders Pettersson, Thomas Lundqvist, Anna Dahlgren, Anders Sågström
Abstract: The present invention relates to a sustained release medical composition comprising an active pharmaceutical ingredient and a geopolymeric binder. Preferably the active pharmaceutical ingredient is combined with the geopolymeric binder during the formation of that binder.
Abstract: There is provided a sustained-release pharmaceutical composition comprising a solid, continuous network comprising an excipient with a high mechanical strength, which network also comprises pores, within which pores is interspersed a mixture of an active ingredient and a film-forming agent, characterized in that said pores are formed during the production of the composition. Compositions of the invention find particularly utility as abuse-resistant formulations comprising opioid analgesics that may be employed in the treatment of chronic pain.
Type:
Grant
Filed:
March 2, 2010
Date of Patent:
April 18, 2017
Assignee:
Emplicure AB
Inventors:
Susanne Bredenberg, Anna Dahlgren, Anders Sågström, Håkan Engqvist
Abstract: The present invention relates to a sustained release medical composition comprising an active pharmaceutical ingredient and a geopolymeric binder. Preferably the active pharmaceutical ingredient is combined with the geopolymeric binder during the formation of that binder.