Abstract: The present invention relates to a modified-release composition comprising orlistat and acarbose, comprising individually distinct parts with different release patterns: a) a first part, G1, comprising from about 5 to about 70% w/w of the total dose of acarbose, b) a second part, G2A, comprising from about 30 to about 95% w/w of the total dose of acarbose, c) a third part, G2B, comprising from about 10 to about 90% w/w of the total dose of orlistat, and d) a fourth part, G3, comprising from about 10 to about 80% w/w of the total dose of orlistat, and the total concentration of acarbose and orlistat, respectively, in the composition is 100% w/w.
Type:
Grant
Filed:
January 24, 2020
Date of Patent:
May 7, 2024
Assignee:
EMPROS PHARMA AB
Inventors:
Göran Alderborn, Anders Forslund, Ulf Holmbäck, Hans Lennernäs, Jan Stefan Persson Grudén
Abstract: The present invention relates to a modified-release composition comprising orlistat and acarbose, comprising individually distinct parts with different release patterns: a) a first part, G1, comprising from about 5 to about 70% w/w of the total dose of acarbose, b) a second part, G2A, comprising from about 30 to about 95% w/w of the total dose of acarbose, c) a third part, G2B, comprising from about 10 to about 90% w/w of the total dose of orlistat, and d) a fourth part, G3, comprising from about 10 to about 80% w/w of the total dose of orlistat, and the total concentration of acarbose and orlistat, respectively, in the composition is 100% w/w.
Type:
Application
Filed:
January 24, 2020
Publication date:
July 23, 2020
Applicant:
EMPROS PHARMA AB
Inventors:
Göran Alderborn, Anders Forslund, Ulf Holmbäck, Hans Lennernäs, Jan Stefan Persson Grudén
Abstract: The present invention relates to a modified-release composition comprising orlistat and acarbose, comprising individually distinct parts with different release patterns: a) a first part, G1, comprising from about 5 to about 70% w/w of the total dose of acarbose, b) a second part, G2A, comprising from about 30 to about 95% w/w of the total dose of acarbose, c) a third part, G2B, comprising from about 10 to about 90% w/w of the total dose of orlistat, and d) a fourth part, G3, comprising from about 10 to about 80% w/w of the total dose of orlistat, and the total concentration of acarbose and orlistat, respectively, in the composition is 100% w/w.
Type:
Grant
Filed:
December 17, 2015
Date of Patent:
February 18, 2020
Assignee:
EMPROS PHARMA AB
Inventors:
Göran Alderborn, Anders Forslund, Ulf Holmbäck, Hans Lennernäs, Jan Stefan Persson Grudén
Abstract: The present invention relates to a modified-release composition comprising orlistat and acarbose, comprising individually distinct parts with different release patterns: a) a first part, G1, comprising from about 5 to about 70% w/w of the total dose of acarbose, b) a second part, G2A, comprising from about 30 to about 95% w/w of the total dose of acarbose, c) a third part, G2B, comprising from about 10 to about 90% w/w of the total dose of orlistat, and d) a fourth part, G3, comprising from about 10 to about 80% w/w of the total dose of orlistat, and the total concentration of acarbose and orlistat, respectively, in the composition is 100% w/w.
Type:
Application
Filed:
December 17, 2015
Publication date:
December 21, 2017
Applicant:
EMPROS PHARMA AB
Inventors:
Göran Alderborn, Anders Forslund, Ulf Holmbäck, Hans Lennernäs, Jan Stefan Persson Grudén