Patents Assigned to Enhance Pharmaceuticals, Inc.
  • Patent number: 6436428
    Abstract: Provided herein is a novel and useful device and method for locally delivering and controllably releasing oxybutynin in the cervical region of a female. A device of the invention comprises a ring comprising trifluoropropylmethyl/dimethyl siloxane elastomer. A pharmaceutical composition comprising oxybutynin and an excipient is placed within a bore located in the ring, wherein the bore runs from the surface of the ring into the ring. The ring has a sufficient size such that it can be inserted into the vaginal canal of a female. A cap comprising is placed over the bore at the surface of the ring in order to contain the pharmaceutical composition within the bore. When the ring is inserted into the vaginal canal, the trifluoropropylmethyl/dimethyl siloxane elastomer controllably releases and locally delivers a therapeutically effective amount of oxybutynin to the detrusor muscle to treat the female's urinary incontinence.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: August 20, 2002
    Assignee: Enhance Pharmaceuticals, Inc.
    Inventors: Anu Mahashabde, Martha Francine Kay, Donald F. Koelmel
  • Patent number: 6394094
    Abstract: Thermoset polymer controlled release devices are produced by an injection molding of two or more polymers in a mold to produce a core surrounded by a sheath. The polymers may be injected sequentially or simultaneously.
    Type: Grant
    Filed: May 3, 1999
    Date of Patent: May 28, 2002
    Assignee: Enhance Pharmaceuticals, Inc.
    Inventors: Michelle McKenna, Angela Reid-Haqq, John F. Cline, Edward J. Gabrielski