Patents Assigned to EpiCept Corporation
  • Pharmaceutical compounds as activators of caspases and inducers of apoptosis and the use thereof
    Patent number: 7842805
    Abstract: Disclosed are 1-arylamino-phthalazines, 4-arylamino-benzo[d][1,2,3]triazines, and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: November 30, 2010
    Assignees: Myrexis, Inc., EpiCept Corporation
    Inventors: Sui Xiong Cai, Mark B. Anderson, Adam Willardsen, Songchun Jiang, Robert J. Halter, Rachel Slade, Yevgeniya Klimova
  • Intradermal-penetration agents for topical local anesthetic administration
    Patent number: 6746689
    Abstract: A non-invasive and non-systemic method for administering a local anesthetic. The method comprises topical application of a local anesthetic in combination with an intradermal-penetration agent selected from the group consisting an aloe composition, a triglyceride, and a mixture thereof.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: June 8, 2004
    Assignee: EpiCept Corporation
    Inventors: Wilfried Fischer, Petra Huber, Paul Mason
  • Topical compositions and methods for treating pain
    Publication number: 20040076648
    Abstract: Topical compositions and methods for treating pain. The invention provides oil-in-water emulsions comprising an antidepressant; an NMDA-receptor antagonists; a lipophilic component; water; and a surfactant. The compositions induce a local-anesthetic effect when topically administered to intact skin thereby treating or preventing pain, for example, neuropathic pain.
    Type: Application
    Filed: September 25, 2003
    Publication date: April 22, 2004
    Applicant: EpiCept Corporation
    Inventors: Robert O. Williams, Feng Zhang
  • Local prevention or amelioration of pain from surgically closed wounds
    Publication number: 20040058994
    Abstract: A non-invasive and non-systemic method for intradermal prevention OR amelioration of pain from a surgically closed wound is disclosed. The method comprises topical delivery of a local anesthetic to an exterior surface of a surgically closed wound.
    Type: Application
    Filed: September 25, 2003
    Publication date: March 25, 2004
    Applicant: EpiCept Corporation
    Inventor: R. Douglas Cassel
  • Local prevention or amelioration of pain from surgically closed wounds
    Patent number: 6645521
    Abstract: A non-invasive and non-systemic method for intradermal prevention OR amelioration of pain from a surgically closed wound is disclosed. The method comprises topical delivery of a local anesthetic to an exterior surface of a surgically closed wound.
    Type: Grant
    Filed: May 3, 2002
    Date of Patent: November 11, 2003
    Assignee: EpiCept Corporation
    Inventor: R. Douglas Cassel
  • Topical compositions and methods for treating pain
    Patent number: 6638981
    Abstract: Topical compositions and methods for treating pain. The invention provides oil-in-water emulsions comprising an antidepressant; an NMDA-receptor antagonists; a lipophilic component; water; and a surfactant. The compositions induce a local-anesthetic effect when topically administered to intact skin thereby treating or preventing pain, for example, neuropathic pain.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: October 28, 2003
    Assignee: EpiCept Corporation
    Inventors: Robert O. Williams, Feng Zhang
  • Methods and compositions for treating pain of the mucous membrane
    Patent number: 6509028
    Abstract: Compositions useful for long-lasting pain relief from mucosal damage, such as mucosal inflamation, abrasions, ulcerations, lesions, trauma and incisions, without significant systemic absorption. The compositions of the invention are particularly suitable for application to the mucous membrane of the nasal cavity and buccal cavity. To relieve pain, the compositions or the invention are topically applied directly to the affected area.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: January 21, 2003
    Assignee: EpiCept Corporation
    Inventors: Robert O. Williams, Feng Zhang, John J. Koleng, Gavril W. Pasternak, Yuri A. Kolesnikov
  • Intradermal-penetration agents for topical local anesthetic administration
    Patent number: 6455066
    Abstract: A non-invasive and non-systemic method for administering a local anesthetic. The method comprises topical application of a local anesthetic in combination with an intradermal-penetration agent selected from the group consisting an aloe composition, a triglyceride, and a mixture thereof.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: September 24, 2002
    Assignee: Epicept Corporation
    Inventors: Wilfried Fischer, Katharina Stoeger, Petra Huber
  • Local prevention or amelioration of pain from surgically closed wounds
    Patent number: 6383511
    Abstract: A non-invasive and non-systemic method for intradermal prevention OR amelioration of pain from a surgically closed wound is disclosed. The method comprises topical delivery of a local anesthetic to an exterior surface of a surgically closed wound.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: May 7, 2002
    Assignee: EpiCept Corporation
    Inventor: R. Douglas Cassel