Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
Type:
Grant
Filed:
April 3, 2015
Date of Patent:
May 8, 2018
Assignees:
ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD, DRK BLUTSPENDEDIENST WEST GMBH
Inventors:
Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
Abstract: The present invention relates to imidazolium salts, particularly imidazolium salts of the general formula I as well as the respective carbene metal complexes and their utilization as bioanalytical tags for biomolecules.
Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
Type:
Grant
Filed:
March 18, 2013
Date of Patent:
April 7, 2015
Assignees:
Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
Inventors:
Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
Type:
Grant
Filed:
November 29, 2011
Date of Patent:
May 7, 2013
Assignees:
Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
Inventors:
Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
Type:
Application
Filed:
November 29, 2011
Publication date:
March 22, 2012
Applicants:
DRK BLUTSPENDIENST WEST GMBH, ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD
Inventors:
ANDREAS GREINACHER, JAN WESCHE, JUERGEN BUX, ANGELIKA REIL
Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
Type:
Grant
Filed:
September 3, 2009
Date of Patent:
December 27, 2011
Assignees:
Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
Inventors:
Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
Abstract: The invention relates to a method for coating surfaces with micro- and nanoparticles, the micro- and nanoparticles being chemically bonded to the surface, comprising the steps of pre-treatment of the surface with a plasma method, simultaneous or subsequent application of the micro- and nanoparticles to the surface, and subsequent fixation of the micro and nanoparticles on the surface using a plasma method, characterized in that the fixation of the micro- and nanoparticles takes place with the aid of anisothermal plasmas, the median electrical energy of which lies in the range of the bond dissociation energy of the micro- and nanoparticles, thus allowing the strength of the chemical bond between the surface and the micro- and nanoparticles to be variably set.
Abstract: A decomposition device and a method for decomposing gases with soot or other harmful substances has a processing station using dielectrically hindered discharge. The device has at least two electrodes, one of which is a porous and gas permeable electrode. In order to decompose the gas containing harmful substances, the gas is first introduced into a processing station in which the gas is subjected to plasma processing involving an alternate voltage supply, and from which the gas is let out. The gas is introduced through one end of the processing station formed by the two electrodes.
Type:
Grant
Filed:
January 10, 2000
Date of Patent:
February 11, 2003
Assignee:
Institute fuer Niedertemperatur-Plasmaphysik E. V. An der
Ernst-Moritz-Arndt-Universitaet Greifswald
Inventors:
Walter Best, Johannes Peter Franziskus Conrads, Wolf-Dieter Franke, Siegfried Mueller, Wolfgang Reich