Patents Assigned to Etablissement Francais du Sang
  • PLASMACYTOID DENDRITIC CELL LINE USED IN ACTIVE OR ADOPTIVE CELL THERAPY
    Publication number: 20120020998
    Abstract: The present invention relates to a method for inducing and amplifying specific effectors, which comprises obtaining pulsed plasmacytoid dendritic cells (pDC) by incubation of a pDC line with at least one antigen, the pulsed pDC being subsequently irradiated and brought into contact with peripheral blood mononuclear cells (PBMC), and cultured or injected into an organism. The pulsed and irradiated pDC and the PBMC share at least one major histocompatibility complex (MHC) allele.
    Type: Application
    Filed: May 15, 2009
    Publication date: January 26, 2012
    Applicant: ETABLISSEMENT FRANCAIS DU SANG
    Inventors: Joel Plumas, Caroline Aspord, Laurence Chaperot-Dubonnet
  • USE OF DELEUCOCYTATION FILTERS FOR DEFENSIN PURIFICATION
    Publication number: 20100291629
    Abstract: The invention concerns the use of deleucocytation filters for defensin purification. More precisely, the invention concerns a method for purifying defensins, including the following steps: passing a blood sample on a deleucocytation filter; detaching the cells retained on the deleucocytation filter, inducing exocytosis of the defensins by those cells.
    Type: Application
    Filed: March 27, 2007
    Publication date: November 18, 2010
    Applicant: ETABLISSEMENT FRANCAIS DU SANG
    Inventors: Chantal Fournier-Wirth, Joliette Coste
  • Anti-aurora-A monoclonal antibody, method for obtaining same and uses thereof for diagnosing and treating cancers
    Patent number: 7514231
    Abstract: The invention concerns a monoclonal antibody directed against mammalian aurora-A kinase, the method for obtaining same, as we ll as its uses in cancer diagnosis and prognosis, and in pharmaceutical compositions for cancer treatment.
    Type: Grant
    Filed: June 12, 2003
    Date of Patent: April 7, 2009
    Assignees: Centre National de la Recherche Scientifique, Etablissement Francais du Sang-Bretagne
    Inventors: Claude Prigent, Anne Martin
  • Dendritic cell line
    Patent number: 7341870
    Abstract: The invention relates to plasmacytoid dendritic human cell lines and methods for producing the cell lines. More specifically, the invention relates to the plasmacytoid dendritic human cell line called GEN2.2, which is deposited in the CNCM under number CNCM 1-2938 and the plasmacytoid dendritic human cell line called GEN3, which is deposited in the CNCM under number I-3110. The use of cells from the cell lines is also disclosed.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: March 11, 2008
    Assignee: Etablissement Francais du Sang
    Inventors: Joel Plumas, Laurence Chaperot-Dubonnet
  • Dendritic cell line
    Publication number: 20050272151
    Abstract: The invention relates to plasmacytoid dendritic human cell lines (pDC), methods for the production thereof and to said cells. More specifically, said invention relates to the plasmacytoid dendritic human cell line called GEN2.2 which is deposited in CNCM under number CNCM I-2938. The use of said cells and pharmaceutical compounds containing plasmacytoid dendritic human cells (pDC) are also disclosed.
    Type: Application
    Filed: December 16, 2003
    Publication date: December 8, 2005
    Applicant: ETABLISSEMENT FRANCAIS DU SANG
    Inventors: Joel Plumas, Lawrence Chaperot-Dubonnet