Patents Assigned to Eve Biomedical, Inc.
  • Methods and compositions for nanostructure-based nucleic acid sequencing
    Patent number: 9725763
    Abstract: Provided herein are nanostructure-based sequencing methods and systems. Such methods and systems include contacting an immobilized RNA polymerase with a double-stranded target nucleic acid molecule under sequencing conditions, where the sequencing conditions include the presence of four nucleoside triphosphates, where one of the nucleoside triphosphates is present in a rate-limiting amount; detecting the movement of the target nucleic acid molecule and/or one or more nascent strand(s) through, on or over a nanostructure; repeating the contacting and detecting steps a plurality of times; and determining the sequence of the target nucleic acid molecule based, sequentially, on the presence or absence of a change in the movement in the presence of the at least one nucleoside triphosphate.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: August 8, 2017
    Assignee: Eve Biomedical, Inc.
    Inventors: Theofilos Kosteroglou, Stephanos Papademetriou
  • Rotation-dependent transcriptional sequencing systems and methods of using
    Patent number: 9657343
    Abstract: Provided herein are rotation-dependent transcriptional sequencing methods and systems.
    Type: Grant
    Filed: November 4, 2013
    Date of Patent: May 23, 2017
    Assignee: Eve Biomedical, Inc.
    Inventor: Theofilos Kotseroglou
  • ROTATION-DEPENDENT TRANSCRIPTIONAL SEQUENCING SYSTEMS AND METHODS OF USING
    Publication number: 20140162275
    Abstract: Provided herein are rotation-dependent transcriptional sequencing methods and systems.
    Type: Application
    Filed: November 4, 2013
    Publication date: June 12, 2014
    Applicant: Eve Biomedical, Inc.
    Inventor: Theofilos Kotseroglou
  • Rotation-dependent transcriptional sequencing systems and methods of using
    Patent number: 8574840
    Abstract: Provided herein are rotation-dependent transcriptional sequencing methods and systems.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: November 5, 2013
    Assignee: Eve Biomedical, Inc.
    Inventor: Theofilos Kotseroglou