Abstract: Described herein are bismethylene-17? carbolactone derivatives having progestational and/or antimineralocorticoid and/or aldosterone antagonistic activity. Also described herein are methods of preparing and using these novel compounds.
Type:
Grant
Filed:
March 4, 2009
Date of Patent:
June 14, 2011
Assignee:
Everstra, Inc.
Inventors:
Klaus Nickisch, Pemmaranu N. Rao, James W. Cessac, Anne Marie Simmons