Abstract: The invention relates to a pH-dependent controlled release pharmaceutical composition, comprising a core, and an opioid, wherein the core is coated at least by one coating layer, controlling the release of the pharmaceutical composition, wherein the coating layer comprises a polymer mixture of i) 40-95% by weight, based on dry weight of the polymer mixture, of at least one water insoluble essentially neutral vinyl polymer, and ii) 5-60% by weight, based on dry weight of the polymer mixture, of at least one anionic polymer or copolymer, which is insoluble in a buffered medium below pH 4.0 and soluble at least in the range from pH 7.0 to pH 8.0, characterized in that the coating layer further comprises 110 to 250% by weight of a non-porous inert lubricant, 1 to 35% by weight of a neutral cellulosic compound and 1 to 25% by weight of an emulsifier, each calculated on dry weight of the polymer mixture.

Abstract: The invention relates to a coating composition suitable for the coating of pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerization process, wherein the core of the core/shell polymer composition is formed by a water-insoluble, cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer.

Abstract: A block-copolymer containing at least two different blocks wherein block A contains (meth)acrylate monomers the copolymer having a glass transition temperature of less than 15° C., block B contains (meth)acrylate monomers the copolymer having a glass transition temperature of more than 25° C. being free of thio-containing substances in the polymer chain, characterized in that one block contains at least one photoinitiator chemically bound to the chain.

Abstract: The present invention relates to a process for preparing alkyl methacrylates and their conversion products which can be used in a multitude of chemical synthesis processes which can lead to a wide variety of different further processing products, and to an apparatus for performing this process.

Abstract: The present invention concerns regulating the water content in a process for production of methacrolein. Methacrolein is used in chemical synthesis particularly as an intermediate for production of methacrylic acid, methyl methacrylate or else of active, aroma or flavor chemicals. The present invention is particularly concerned with regulating the water content in a process for production of methacrolein from formaldehyde and propionaldehyde via a Mannich condensation.

Abstract: The present invention provides a solid dosage form including an inner coating located between a core containing a pharmaceutically active ingredient and an outer enteric coating; wherein the inner coating includes a partially neutralized anionic polymeric material, and at least a carboxylic acid having 2 to 16 carbon atoms the salts thereof or mixtures of the acid and its salt; wherein the outer coating includes an anionic polymeric material which is less or not at all neutralized than the material of the inner coating.

Abstract: The present invention relates to a process for producing transparent polymeric films or plastics moldings of particularly high chemical resistance, having more particularly a very good resistance towards oil-in-water and water-in-oil emulsions, and of high optical quality.

Abstract: A 3D extrusion print process for producing multicolored three-dimensional objects is provided. The process produces mechanically stable, multicolored 3D objects with good color definition. The process according to the invention is based on coating, upstream of the printing head, of the polymer strand used for producing the actual object, and on fixing of the coating upstream of entry of the polymer strand into the printing head. Downstream of the extrusion process in the printing head, the coating remains predominantly at the surface of the extruded strand.

Abstract: Provided is an adhesive composition suitable for producing a laminate. The composition contains specified amounts of (a) polyisobutyl methacrylate, isobutyl methacrylate or a mixture thereof, (b) butyl acrylate, (c) polybutyl acrylate, (d) a (meth)acrylate compound and (e) a silicon compound. These components may be in polymerizable form, in polymerized form or in a combination of polymerizable form and polymerized form. The amounts of components (a) to (e) total 100 wt. % and the amount of (b) and (c) represents 30 to 90 wt. %, based on the sum total of components (a) to (e). The composition may optionally further contain from 0.1 to 6 wt. %, based on the total weight of the adhesive composition, of additives different from components (a) to (e) described above.

Abstract: The invention refers to a Process for preparing a bio-resorbable polyester the form of a powder with a bulk density of 0.3 g/ml or more, a tapped density of 0.4 g/ml or more and a specific surface area of 2.0 m2/g or less comprising the steps a. dissolving a bio-resorbable polyester in a first solvent to form a polymer solution, b. contacting the polymer solution with a second solvent which is a non-solvent for the bioresorbable polyester and which is mainly water to result the precipitation of the bio-resorbable polyester in the form of a wet polymer mass, c. pre-drying the wet polymer mass at a temperature below the TgO of the bio-resorbable polyester, d. comminuting the pre-dried polymer mass to polymer particles with a size below 10 mm, e. drying the comminuted polymer particles below the TgO of the bio-resorbable polyester to a residual water content of 1% or less by weight/weight, f.

Abstract: The present invention relates to a process for the production of alpha-hydroxycarboxylic esters by means of alcoholysis of the corresponding alpha-hydroxycarboxamide under heterogeneous catalysis.

Abstract: This invention relates to a process of preparing highly pure, non-yellowing (meth)acrylic acid necessary for high-tech applications requiring long-tem color stability in the presence of amines. Process for the preparation of highly pure, non-yellowing (meth)acrylic acid comprising the steps: f) Condensation of a (meth)acrylic acid-containing gas phase obtained via a gas phase oxidation process of a C4-compound to generate an aqueous (meth)acrylic acid solution g) Separation of the (meth)acrylic acid from the aqueous (meth)acrylic acid solution to obtain crude (meth)acrylic acid h) Rectification of the crude (meth)acrylic acid to obtain pure (meth)acrylic acid via a sidestream outlet of the rectification column i) Treatment of the pure (meth)acrylic acid generated in step c) with an ion exchange resin j) Distillation of the (meth)acrylic acid generated in step d).

Abstract: The present invention relates to a catalyst for reacting carbonitriles with water, wherein the catalyst comprises at least 60% by weight of manganese dioxide with an empirical formula MnOx where x is in the range from 1.7 to 2.0, and at least one plasticizer. The present invention further relates to a process for preparing the catalysts detailed above and to a process for preparing carboxamides by reacting carbonitriles with water in the presence of the present catalyst.

Abstract: The invention relates to a modified fused deposition modeling process for production of multicolored three-dimensional objects. More particularly, the invention relates to a 3D printing process with which 3D objects with particularly good color appearance compared to the prior art can be produced. The process according to the invention is based on coloring of the polymer strand used for production of the actual object in the nozzle, and on using a mixing apparatus which comprises a plurality of injection needles, a static mixer or a dynamic mixer.

Abstract: The present invention relates to a novel process for producing ceramic materials, in particular refractory materials having a reduced relative density. In particular, the invention relates to a process for producing light, refractory materials having non-contiguous pores based on shaped and unshaped materials. These materials can be used as working lining in high-temperature applications. The process is based on the production of spherical, closed and isolated pores in the microstructure of the material. The pores having a pore diameter which can be set in a targeted manner are generated by use of polymer particles, in particular polymethacrylates, in particular polymers or copolymers prepared by means of suspension polymerization, as pore formers which can be burnt out. The polymers or copolymers are present in the form of small spheres having a defined diameter.

Abstract: The present invention relates to a pharmaceutical or nutraceutical preparation comprising a) a core containing a pharmaceutically or nutraceutically active substance; and b) an inner controlling layer surrounding the core comprising i) one or a mixture of a plurality of (meth)acrylate copolymers bearing a cationic group or a group that can be converted to a cationic group; and ii) one or a mixture of a plurality of polymers or copolymers bearing an anionic group or group that can be converted to an anionic group; and c) an outer controlling layer comprising one or a mixture of a plurality of polymers or copolymers bearing an anionic group or group that can be converted to an anionic group and to tablets or capsules comprising same.

Abstract: The present invention relates to a process for purifying monomers, by evaporating at least a portion of the monomers present in a starting composition and then condensing it, which is characterized in that at least a portion of the starting composition is evaporated in a short-path evaporator, the mass flow density of the vapors {dot over (m)} being selected according to the relation (I) m . ? 1800 ? kg · K mbar · m 2 · h · kg kmol · p i · ( M ~ T ) 0.5 ( I ) in which {tilde over (M)} is the average molar mass of the vapors in the short-path evaporator in kg/kmol T is the temperature of the vapors in K pi is the pressure in the short-path evaporator in mbar {dot over (m)} is the mass flow density of the vapors in kg/(m2·h). A further aspect of the present invention is a plant for performing the process.

Abstract: The present invention relates to a process for producing coated mouldings with fully or partly structured surfaces. The present invention additionally describes a system for performing this process.

Abstract: The invention relates to light guide plates, which are suitable for backlighting LCD monitors as well as information and advertising signs and which are illuminated at the edges and re-emit the light fed at the edges via at least one of the two surfaces located perpendicular to the edges. For the light of a light source that is fed at the edges to be able to leave the light guide plate again via one of the surfaces by overcoming total reflection, the light rays in the light guide plate have to be deliberately deflected. At one of the two surfaces of the light guide plate, the light guide plates are provided with optical impurities (2), which are protected against damage by a film (5). Furthermore, a method for the simplified application of said impurities is provided.

Abstract: The present invention relates to an apparatus for metering flowable media or gases, and to the use thereof.