Abstract: A medical lancing device including an independent drive core mechanism incorporating all or a substantial portion of the functional components of the lancing device, whereby the independent drive core mechanism can be incorporated into multiple different external housing configurations for more efficient design and manufacture. Axial adjustment of the position of the independent drive core mechanism within the housing provides lancing penetration depth control.

Abstract: A lancing device and a cartridge of lancets are operable to sequentially advance each lancet to an active position for use in sampling a bodily fluid. An alignment mechanism precisely aligns the lancets in the active position to promote smooth operation and prevent jamming. The alignment mechanism includes at least one register element and at least one spring-biased element movable between engaged and retracted positions. In an example embodiment, one spring-biased arm extends from the lancing-device housing and includes a protrusion, and a series of recessed register surfaces are defined in a carrier for the lancets. In the engaged position, the spring-biased protrusion fully mates with the register recess under the spring-biasing influence to precisely align the active lancet. And in the retracted position, the spring-biased protrusion is deflected from engagement with the register recess as the carrier is advanced to advance a fresh lancet into the active position.

Abstract: A lancing device including a replaceable multi-lancet cartridge The lancing device includes a drive mechanism an activation mechanism, and an advancing mechanism The advancing mechanism includes a linear-pull slide controls an indexing mechanism, a charger mechanism, and a cap-displacement mechanism. The indexing mechanism sequentially advances the lancets to an active position The charger mechanism charges the drive mechanism and removes the lancet caps And the cap-displacement mechanism moves the separated caps from the lancing stroke path The activation mechanism then releases the charged lancet to traverse the lancing stroke path to pierce the subject's skin Some embodiments include an anti-reverse mechanism to prevent reuse of the lancets, and some include an emergency lancet reuse mechanism that permits emergency reuse of the last lancet And some embodiments include a movable depth-control wall for providing control and adjustment of the lancing penetration depth.

Abstract: Lancing devices are disclosed having a carriage slidably disposed within the housing and a lancet carrier configured to directly receive and hold the lancet. The lancet carrier is engaged within the carriage and movable relative to and independently of the carriage between a forward incision position and a rearward cocked position. A trigger assembly has a user accessible first portion and a second portion attached to the carriage and movable with the carriage along the longitudinal axis. The second portion is configured to maintain the lancet carrier in the rearward cocked position and the first portion is configured to release the lancet carrier from the rearward cocked position.

Abstract: Provided are devices, systems, and methods for targeted administration of therapeutic agents to a subject. For example, provided are devices, systems, and methods for targeting the administration of peri-urethral bulking agents.

Abstract: A single-use safety lancet having a housing, a triggering mechanism, and at least one grip. The housing contains a drive system and includes a proximal end and a distal end. The triggering mechanism is coupled to the proximal end of the housing and is operable to activate a lancet stroke. The at least one grip extends from the housing and is operable to permit user interaction therewith.

Abstract: A lancing device including a drive mechanism with a drive spring and a lancet carrier engaged and driven by the drive spring, and further including a lancet with a sharp lancing tip, wherein the lancet floats relative to the carrier and is decoupled from the drive mechanism during at least a portion of a lancing stroke. In one example embodiment the lancet is held in a sled that floats in the carrier, and in another example embodiment the lancet by itself floats in the carrier.

Abstract: Improved lancet configurations and protective lancet endcap configurations are disclosed. In example forms, one or more flexing cantilevers project from the lancet body for coupling with a cooperating receiver of a lancing device. A gripping handle extends from a sterility cap for ease of removal from and replacement over the lancet tip. A lancet body has a smoothly curved wave contour with at least one crest and at least one trough for engagement with a cooperating receiver of a lancing device.

Abstract: A lancing device having a housing with a proximal end, a distal end and a longitudinal axis. The lancing device also has a lancet carrier translatably supported with respect to the housing. The lancet carrier has a proximal end and a distal end. The lancing device additionally has a depth-control mechanism with a positioning tab adapted to engage the housing, and a tether secured with respect to the positioning tab and the lancet carrier.

Abstract: Lancets and methods of use are provided. Embodiments include lancets including a sleeve mounted to an elongated body having a needle terminating in a sharp tip.

Abstract: A multi-use micro-sampling or lancing device having an outer housing, a lancet holder that engages a lancet and constrains the lancet along a controlled and pre-defined path of travel during the lancing stroke, and a drive mechanism with a pair of opposed, off-axis torsion springs working in tandem to drive and return the lancet holder through its lancing stroke.

Abstract: Lancets and methods of use are provided. Embodiments include lancets including a sleeve mounted to an elongated body having a needle terminating in a sharp tip.

Abstract: A lancing device is provided for use with a removable lancet. The lancing device includes a housing and a lancet carrier slidably disposed within the housing and adapted to receive the lancet. A user-actuated ejection slide is mounted to the housing to eject the lancet from the lancet carrier. A locking member is pivotally mounted to the housing. As the ejection slide moves forward, it rotates the locking member to block forward movement of the lancet carrier during ejection. The locking member is configured so that substantially all of the force exerted on it by the lancet carrier is transmitted to the housing via the pivotal mounting.

Abstract: A housing and an internal mechanism including a blade, a dual-link drive mechanism, and a trigger. The blade is driven by the drive mechanism through a rotating and translating slicing motion that defines a sampling sequence, from a first retracted position to an extended position to a second retracted position. The dual-link drive mechanism includes a blade link arm coupled to the blade, a rotary drive link arm that drives the blade arm, a drive spring that drives the a rotary drive arm, and a cam-and-follower mechanism that guides the blade arm as it is driven by the rotary drive arm. The trigger is operable to release the dual-link drive mechanism to propel the blade through the sampling sequence. And a sterility cap protects the blade and prevents operation of the device prior to removal.

Abstract: Lancing devices are disclosed having a carriage slidably disposed within the housing and a lancet carrier configured to directly receive and hold the lancet. The lancet carrier is engaged within the carriage and movable relative to and independently of the carriage between a forward incision position and a rearward cocked position. A trigger assembly has a user accessible first portion and a second portion attached to the carriage and movable with the carriage along the longitudinal axis. The second portion is configured to maintain the lancet carrier in the rearward cocked position and the first portion is configured to release the lancet carrier from the rearward cocked position.

Abstract: Lancing devices for use with removable lancets having sharp tips are provided. Embodiments include an interlock within the housing that blocks insertion of the lancet when the device is already cocked.

Abstract: A lancing device has a housing, an activation/retraction control assembly, and a lancet. The control assembly and the housing have cooperating engagement structures such as detents that disengage after a predetermined launch force is applied to the control assembly. In this way, the lancet is driven to its puncturing position without the use of a drive spring. In addition, the control assembly and the lancet have cooperating releasable engagement structures such as notched sections and tamped protrusions that disengage when the lancet reaches its puncturing position, thereby freeing the lancet from the control assembly. And the control assembly has angled retraction structures that engage the freed lancet to bias it back safely into the housing.

Abstract: A guidance mechanism for a lancing device. The guidance mechanism includes a piston having a shaft, a plurality of wings or fins extending from the shaft, a plurality of sliding engagement structures, and a lancet holder; and a chassis having a body, a plurality of longitudinal slits or cutouts, a plurality of elongated engagement structures, and an end aperture. The piston slides within the chassis, and the wings/fins engage within the slits/cutouts, allowing for linear longitudinal guidance of the piston within the chassis.