Abstract: The present invention relates to compounds that act as DUX4 repressors, suitable for the treatment of diseases related to DUX4 expression, such as muscular dystrophies. It also relates to use of such compounds, or to methods of use of such compounds.
Type:
Application
Filed:
November 27, 2020
Publication date:
August 31, 2023
Applicant:
Facio Intellectual Property B.V.
Inventors:
Pui Leng Loke, Joris Herman De Maeyer, Robert David Matthew Pace, Simon Fletcher Elwood, Gregory Foulkes, Andrew Anighoro, Ainoa Rueda-Zubiaurre, Jonathan Philip Richards, Adam James Davenport, Cristina Lecci, Anthony Paul Dickie, Gerd Schnorrenberg
Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies. It also relates to use of such compounds, or to methods of use of such compounds.
Type:
Application
Filed:
November 27, 2020
Publication date:
February 16, 2023
Applicant:
Facio Intellectual Property B.V.
Inventors:
Pui Leng Loke, Joris Herman De Maeyer, Robert David Matthew Pace, Gregory Foulkes, Ainoa Rueda-Zubiaurre, Simon Fletcher Ellwood, Adam James Davenport, Anthony Paul Dickie, Gerd Schnorrenberg
Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies. It also relates to use of such compounds, or to methods of use of such compounds.
Type:
Application
Filed:
June 12, 2020
Publication date:
July 21, 2022
Applicant:
Facio Intellectual Property B.V.
Inventors:
Joris De Maeyer, Marcus Geese, Sebastian Monecke, Rolf Hirsch, Pui Leng Loke
Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies, wherein the disease is facioscapulohumeral muscular dystrophy (FSHD). It also relates to use of such compounds, or to methods of use of such compounds.
Type:
Application
Filed:
January 13, 2022
Publication date:
July 21, 2022
Applicant:
Facio Intellectual Property B.V.
Inventors:
Joris De Maeyer, Marcus Geese, Martin Schneider, Sebastian Monecke, Alexander Kaever, Monika Ermann, Timothy Robin James
Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies. It also relates to use of such compounds, or to methods of use of such compounds.
Type:
Application
Filed:
December 13, 2018
Publication date:
June 17, 2021
Applicant:
Facio Intellectual Property B.V.
Inventors:
Joris De Maeyer, Marcus Geese, Martin Schneider, Sebastian Monecke, Alexander Kaever, Monika Ermann, Timothy Robin James
Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies, wherein the disease is facioscapulohumeral muscular dystrophy (FSHD). It also relates to use of such compounds, or to methods of use of such compounds.
Type:
Grant
Filed:
December 12, 2018
Date of Patent:
April 13, 2021
Assignee:
Facio Intellectual Property B.V.
Inventors:
Joris de Maeyer, Marcus Geese, Martin Schneider, Sebastian Monecke, Alexander Kaever, Monika Ermann, Timothy Robin James
Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies, wherein the disease is facioscapulohumeral muscular dystrophy (FSHD). It also relates to use of such compounds, or to methods of use of such compounds.
Type:
Application
Filed:
December 12, 2018
Publication date:
June 13, 2019
Applicant:
Facio Intellectual Property B.V.
Inventors:
Joris de Maeyer, Marcus Geese, Martin Schneider, Sebastian Monecke, Alexander Kaever, Monika Ermann, Timothy Robin James