Abstract: This invention relates to a method of and means for conveying and measuring gases for gas analysis operations by means of a pump, which conveys the gas with constant volume per working cycle. The means for this purpose, as used in connection with gas analysis instruments, consists of a cyclically operating gas delivery pump with an electric motor drive which is connected to a frequency transmitter for pre-setting the speed of rotation.
Abstract: This invention relates to inhibitors for glycosidehydrolases derived from bacteria of the order Actinomycetales, means for their production comprising cultivation of a microorganism of the order Actinomycetales in appropriate nutrient solutions under conditions most favorable to growth and production of the enzyme inhibitor and recovering, as a new product, glycoside-hydrolase enzyme inhibitors, from the culture as well as the use of said enzyme inhibitors in pharmaceutically acceptable therapeutic compositions in the treatment of conditions indicating obesity, diabetes, pre-diabetes, gastritis, gastric ulcer, hyperlipidemia (arteriosclerosis) and the like.
Type:
Grant
Filed:
July 31, 1974
Date of Patent:
March 22, 1977
Assignee:
Farbenfabriken Bayer Aktiengesellschaft
Inventors:
Werner Frommer, Walter Puls, Dietmar Schafer, Delf Schmidt
Abstract: This invention relates to inhibitors for glycoside-hydrolases derived from bacteria of the order Actinomycetales, means for their production comprising cultivation of a microorganism of the order Actinomycetales in appropriate nutrient solutions under conditions most favorable to growth and production of the enzyme inhibitor and recovering, as a new product, glycoside-hydrolase enzyme inhibitors, from the culture as well as the use of said enzyme inhibitors in pharmaceutically acceptable therapeutic compositions in the treatment of conditions indicating obesity, diabetes, pre-diabetes, gastritis, gastric ulcer, hyperlipidemia (arteriosclerosis) and the like.
Type:
Grant
Filed:
July 31, 1974
Date of Patent:
April 20, 1976
Assignee:
Farbenfabriken Bayer Aktiengesellschaft
Inventors:
Werner Frommer, Walter Puls, Dietmar Schafer, Delf Schmidt
Abstract: An inhibitor for .alpha.-amylases, particularly pancreas amylase, is extracted from wheat, as for example, wheat flour or wheat gluten, by means of aqueous alcoholic solutions of lower alcohols of 1 to 3 carbon atoms, or dilute aqueous acid solutions having a pH of from 1 to 5, or of mixtures of the aqueous alcoholic solutions with dilute acids, and separating the desired amylase inhibitor contained in the aqueous phase from the extraction mixture by known methods. The amylase inhibitor thus obtained is particularly effective against pancreas amylase and is indicated as a therapeutic agent for the treatment of conditions resulting from alimentary hyperglycemia, such as adiposity, arteriosclerosis, diabetes and prediabetes.