Abstract: A method comprises measuring the execution time T1 for a problem to be solved with a program being run by a single processor, measuring the execution time TM and TS of MIMD and SIMD program fragments being run by a single processor and a single accelerator correspondingly, determining the specific acceleration ? of the execution time for an SIMD program fragment being run by a single accelerator in comparison with the execution time for the fragment being run by a single processor, determining a portion of the execution time for an MIMD fragment being run by a single processor and a portion of the execution time for an SIMD fragment being run by a single processor and adjusting the quantity of processors or accelerators comprised in a hybrid computing system structure according to the data obtained.