Abstract: A zipper carton includes a first panel having an elongated slot extending therethrough, the slot having a length extending between opposing ends. A locking panel assembly includes a removable zipper tear strip and a locking tab having a linear length that is greater than the length of the slot. The locking tab includes a base projecting from the removable zipper tear strip and a first retention flap projecting from the base and being foldable relative to the base. The locking tab is configured so that when the first retention flap is folded from a relaxed position to a folded position, at least a portion of the locking tab including the first retention flap can be slid through the slot and after the first retention flap passes through the slot, the retention flap automatically resiliently rebounds at least partially toward the relaxed position so as to block retraction of the locking tab from the slot.

Abstract: A vial blinding assembly includes a vial having a bottle with a constricted neck and an annular shoulder that inwardly extends; a stopper disposed on an opening of the bottle and having a septum with a top surface; and a retainer securing the stopper to the bottle. A tubular blinding shell encircles a compartment that extends between a first end with an inlet opening and an opposing second end with an access opening. A floor plug is secured to the first end of the blinding shell. The vial is disposed within compartment of the blinding shell with the vial being supported by the floor plug and the neck passing through the access opening so that the top surface of the septum is disposed outside of the compartment of the blinding shell, the shoulder of the vial having an outside diameter larger than a diameter of the access opening.

Abstract: A rack for holding flat panels containing PCM while the flat panels are conditioned and a method of conditioning the flat panels. The rack includes a frame structure defining an interior through which a conditioning air flow is directed. The interior includes a plurality of vertically spaced shelves for supporting the flat panels in a vertically spaced apart arrangement. The shelves are configured to hold the flat panels with at least a majority of their upper and lower surfaces in contact with the conditioning air flow. A conditioning method includes arranging the flat panels in a spaced apart array in the rack to create air flow channels between adjacent surfaces of the flat panels. Air is circulated between and in contact with the flat panels at a first temperature sufficient to bring the temperature of the PCM in each flat panel at least closer to a required temperature range.

Abstract: A passive cold storage container system includes a container bounding a storage area with at least one heat sink module disposed therein. A first storage unit having a compartment is also disposed within the storage area. A first tray is removably disposed within the compartment of the first storage unit, the first tray having a floor with a top surface and a plurality of spacers upstanding from the top surface of the floor and being spaced apart. A plurality of medicinal carriers are disposed on the first tray between the spacers, each medicinal carrier housing a medicinal preparation. A first retention plate is disposed within the compartment of the first storage unit and is positioned over the plurality of medicinal carriers.

Abstract: An attachable panel assembly includes a replacement panel having a mounting panel and a closure panel projecting from the mounting panel. The closure panel has an attachment portion and a removable zipper tear strip disposed between the attachment portion and the mounting panel. The panel assembly also includes a first adhesive layer disposed on the mounting panel and a second adhesive layer disposed on the attachment portion of the replacement closure panel, the first adhesive layer and the second adhesive layer being disposed on opposing sides of the replacement panel. A resealable carton system includes the panel assembly attached or attachable to a carton body of a carton assembly by means of the first adhesive layer. The carton assembly can be sealed by closing an inner closure panel of the carton assembly and folding the replacement closure panel so that the second adhesive binds to the inner closure panel.

Abstract: A zipper carton assembly for receiving a blinded trial product includes a carton body having an encircling side wall, a floor, and a covering that together bound an inner compartment for receiving the blinded trial product, an adhesive layer disposed on a portion of the covering, and a removable liner covering at least a portion of adhesive layer. The covering includes an inner closure panel that folds into a closed position to selectively cover an access opening to the inner compartment and an opposing outer closure panel that folds over and is secured to a portion of the inner closure panel by means of the adhesive layer. The removable liner covers the adhesive layer until the zipper carton assembly is ready for sealing. The sealed zipper carton assembly can be opened by removing a zipper tear strip formed in a portion of the covering.

Abstract: Methods and systems for providing information relating to the specialized handling of a package, and articles contained within the package. Data relating to a package containing an article that requires specialized handling is associated with a unique identifier and stored in a database. The unique identifier is also included in a machine readable code affixed to the package. A recipient of the package scans the machine readable code using an application downloaded into a mobile device, which extracts the unique identifier from the machine readable code and transmits a request to the database. The database may then identify data stored in the database that relates to the article based on the unique identifier, and transmit the data to the mobile device for display to the recipient. The data may include instructions on how to unpack the package, and how to store or use articles contained within the package.

Abstract: Methods and systems for providing information relating to specialized handling of a package, and articles contained within the package. Data relating to a package containing an article that requires specialized handling is associated with a unique identifier and stored in a database. The unique identifier is also included in a machine readable code affixed to the package. A recipient of the package scans the machine readable code using an application downloaded into a computing device, which extracts the unique identifier from the machine readable code and transmits a request to the database. The database may then identify data stored in the database that relates to the article based on the unique identifier, and transmit the data to the computing device for display to the recipient. The data may include a packing list, instructions for how to unpack the package, and how to store or use articles contained within the package.

Abstract: A blinding tube assembly for concealing a drug delivery tube includes a blinding tube having a tubular sleeve that bounds a compartment and a tubular dispersing stem projecting from an end of the sleeve. A drug delivery tube is inserted into the compartment through and access opening opposite the dispersing stem. The drug delivery tube has a tubular body and a dispensing stem extending from a drug delivery end thereof. A tubular bushing is disposed about the dispensing stem such that when the drug delivery tube is inserted, the dispensing stem is received into the dispersing stem of the blinding tube with the bushing disposed therebetween. An annular end face of the dispensing stem is not visible through a dispersing opening in the dispersing stem from outside the blinding tube.

Abstract: Methods and systems for providing information relating to the specialized handling of a package, and articles contained within the package. Data relating to a package containing an article that requires specialized handling is associated with a unique identifier and stored in a database. The unique identifier is also included in a machine readable code affixed to the package. A recipient of the package scans the machine readable code using an application downloaded into a mobile device, which extracts the unique identifier from the machine readable code and transmits a request to the database. The database may then identify data stored in the database that relates to the article based on the unique identifier, and transmit the data to the mobile device for display to the recipient. The data may include instructions on how to unpack the package, and how to store or use articles contained within the package.

Abstract: A shipper having an outer housing with a temperature sensitive payload and a temperature/location tracker disposed therein. The outer housing has a body having an interior surface bounding a compartment that is accessed through an opening. A first panel is coupled with the body and configured to extend over at least a portion of the opening, with a first access port extending through the first panel. The payload and temperature/location tracker are disposed within the compartment of the body. The temperature/location tracker includes a first temperature probe, a GPS receiver, a cellular modem, and a GPS antenna. The GPS antenna is disposed so as to be aligned with the first access port when the shipper is in a fully assembled state such that the GPS antenna is directly accessible through the first access port. The temperature/location tracker monitors and periodically transmits temperature and location values of the shipper over a cellular communication network.

Abstract: A method for splitting tablets includes positioning a plurality of tablets onto a supporting structure. Each of the plurality of tablets are then substantially simultaneously split into at least two parts. Finally, if desired, the at least two parts of each tablet are dispensed into a compartment of a corresponding one of a plurality of first capsule portions.

Abstract: A shipper having an outer housing with a temperature sensitive payload and a temperature/location tracker disposed therein. The outer housing has a body having an interior surface bounding a compartment that is accessed through an opening. A first panel is coupled with the body and configured to extend over at least a portion of the opening, with a first access port extending through the first panel. The payload and temperature/location tracker are disposed within the compartment of the body. The temperature/location tracker includes a first temperature probe, a GPS receiver, a cellular modem, and a GPS antenna. The GPS antenna is disposed so as to be aligned with the first access port when the shipper is in a fully assembled state such that the GPS antenna is directly accessible through the first access port. The temperature/location tracker monitors and periodically transmits temperature and location values of the shipper over a cellular communication network.

Abstract: A method for splitting tablets includes positioning a plurality of tablets onto a supporting structure. Each of the plurality of tablets are then substantially simultaneously split into at least two parts. Finally, if desired, the at least two parts of each tablet are dispensed into a compartment of a corresponding one of a plurality of first capsule portions.

Abstract: The invention relates to child-resistant package having a shell with a first locking part and a tray having blister card coupled to a tether having a second locking part. In a closed position the first locking part engages the second locking part to limit the movement of the tray relative to the shell. A release part is provided and is operable to disengage the first and second locking parts and free the tray to move from the closed position to an open position.