Abstract: A description is given of new pharmaceutical compositions containing cyclosporine, combined with a carrier comprising at least a derivative of &agr;-glycerophosphoric acid, such as &agr;-glycerophosphorylcholine, &agr;-glycerophosphorylserine, &agr;-glycerophosphorylethanolamine and &agr;-glycerophosphoryl-myo-inositol, which allow cyclosporine bioavailability to significantly increase.
Abstract: Deacylated glycerophospholipids, such as L-.alpha.-glycerylphosphorylcholine, L-.alpha.-glycerylphosphorylethanolamine, L-.alpha.-glycerylphosphorylserine, L-.alpha.-glycerylphosphoryl-D-myo-inositol are effective for topical use and may be incorporated into cosmetic or pharmaceutical compositions.
Type:
Grant
Filed:
September 28, 1994
Date of Patent:
June 10, 1997
Assignee:
Flarer S.A. Pharmaceutical Fine Chemicals
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