Abstract: In some embodiments, the invention includes therapeutic combinations of antiviral active pharmaceutical ingredients and anti-inflammatory active pharmaceutical ingredients, including steroids, and methods of using of the therapeutic compositions in the treatment of viral infections.
Abstract: Disclosed are stable compositions comprising povidone-iodine and a steroid, and methods of making and using such compositions. Also disclosed herein are stable compositions comprising povidone-iodine and an NSAID, and methods of making and using such compositions.
Type:
Application
Filed:
May 11, 2012
Publication date:
February 5, 2015
Applicant:
FORESIGHT BIOTHERAPEUTICS, INC.
Inventors:
Jason Stein, Michael Weiser, Joseph A. Capriotti, Bo Liang, C. Michael Samson
Abstract: The invention includes a preserved ophthalmic preparation comprising povidone-iodine (PVP-I) at a concentration sufficient to preserve the ophthalmic preparation, and at least one member selected from the group consisting of a steroidal anti-inflammatory compound, a non-steroidal anti-inflammatory compound, an antibacterial compound, an anti-allergy compound, and an anti-glaucoma compound. The invention also includes adding PVP-I to an ophthalmic composition in order to preserve the composition, wherein the PVP-I is added at a concentration sufficient to preserve the composition.
Type:
Application
Filed:
May 16, 2013
Publication date:
September 26, 2013
Applicant:
FORESIGHT BIOTHERAPEUTICS, INC.
Inventors:
Bo Liang, Joseph A. Capriotti, C. Michael Samson, Jason Stein, Michael Weiser, Mark Abelson
Abstract: Disclosed are compositions and methods comprising povidone-iodine and a cooling-effective amount of a chemical agent. The compositions are useful to relieve mild ocular irritation, enhance ocular comfort, and to provide a refreshing effect and improved sensation, when the povidone-iodine solution is applied to the eye.
Type:
Application
Filed:
December 15, 2010
Publication date:
July 11, 2013
Applicant:
FORESIGHT BIOTHERAPEUTICS, INC.
Inventors:
Bo Liang, Joseph A. Capriotti, C. Michael Samson, Jason Stein, Michael Weiser
Abstract: Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.
Type:
Application
Filed:
May 8, 2012
Publication date:
April 11, 2013
Applicant:
Foresight Biotherapeutics, Inc.
Inventors:
Joseph A. Capriotti, Bo Liang, C. Michael Samson, Jason Stein, Michael Weiser
Abstract: The invention includes a preserved ophthalmic preparation comprising povidone-iodine (PVP-I) at a concentration sufficient to preserve the ophthalmic preparation, and at least one member selected from the group consisting of a steroidal anti-inflammatory compound, a non-steroidal anti-inflammatory compound, an antibacterial compound, an anti-allergy compound, and an anti-glaucoma compound. The invention also includes adding PVP-I to an ophthalmic composition in order to preserve the composition, wherein the PVP-I is added at a concentration sufficient to preserve the composition.
Type:
Application
Filed:
June 10, 2009
Publication date:
February 2, 2012
Applicant:
Foresight Biotherapeutics, Inc.
Inventors:
Jason Stein, Bo Liang, C. Michael Samson, Joseph A. Capriotti, Michael Weiser, Mark B. Abelson
Abstract: Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.
Type:
Application
Filed:
September 16, 2011
Publication date:
January 5, 2012
Applicant:
Foresight Biotherapeutics, Inc.
Inventors:
Joseph A. Capriotti, Bo Liang, C. Michael Samson, Jason Stein, Michael Weiser
Abstract: A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g. corneal abrasion, postoperative prophylaxis, post-LASIK/LASEK prophylaxis). Additionally the solution is effective in the prevention of infection and inflammation in the post-operative ophthalmic patient.
Type:
Grant
Filed:
December 7, 2006
Date of Patent:
August 3, 2010
Assignee:
Foresight Biotherapeutics
Inventors:
C. Michael Samson, Bo Liang, Joseph A. Capriotti
Abstract: Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.
Type:
Application
Filed:
February 27, 2009
Publication date:
October 22, 2009
Applicant:
Foresight Biotherapeutics, Inc.
Inventors:
Joseph A. Capriotti, Bo Liang, C. Michael Samson, Jason Stein, Michael Weiser