Abstract: A method for identifying inhibitors of the primary nucleation of amyloid beta aggregation includes providing an A-beta species in solution or in a buffer, and determining the amyloid-beta aggregation, wherein the A-beta species comprises two A-beta monomer units with a linker arranged between the A-beta monomer units is provided. A method for analyzing aggregation of monomers of protein misfolding diseases and a kit are also provided.

Abstract: A solvent-free polymer electrolyte having a polymer matrix which is conductive for lithium ions and a lithium salt, wherein the polymer matrix has at least one pseudo-polyrotaxane which includes at least one linear polymer and at least one ring-shaped molecule, and wherein the lithium salt is arranged in the polymer matrix and is at least partially chemically bonded to the polymer matrix, wherein the polymer matrix includes at least one pseudo-polyrotaxane with at least one completely or partially chemically modified cyclodextrin or at least one completely or partially chemically modified crown ether, in which the present hydroxyl groups of the cyclodextrin, or the scaffold of the crown ether, are/is partly or completely modified by functional groups, wherein the functional groups comprise alkyl, aryl, alkenyl, alkynyl groups (Cn, with n?5), or other short-chain polymer groups having up to 20 repeating units.

Abstract: A coil assembly for use as a transmission and/or receiving coil in an MR system comprises a dipole antenna assembly with multiple dipole antennas. Connection elements are converted from an electrically conductive state to an electrically non-conductive state. In the electrically conductive state, the dipole antennas form a cylindrical volume coil and/or a conductor loop assembly, in particular a flat conductor loop assembly. The connection elements comprise blocking circuits which automatically block when a high-frequency alternating voltage with a frequency corresponding to the blocking frequency of the connection element blocking circuits is applied to the coil assembly.

Abstract: A mounting device for a flat seal of a flange connection that includes a first flange, a second flange, and a flat seal arranged between the flanges. The mounting device includes a clamping jaw for a clearance between the first flange and the second flange. The clamping jaw tapers at an end to a nose for holding the flat seal.

Abstract: The present invention relates to a copolymer containing alternating hydrophobic and hydrophilic units and to the use of said copolymers as carrier for active ingredients through a lipid bilayer, especially a lipid membrane.

Abstract: A device for an MeV-based ion beam analysis of a sample includes a vacuum measurement chamber, having at least one detector and a sample observation unit, a vacuum system for generating a vacuum within the vacuum measurement chamber, and an ion beam tube and a focusing system for focusing an ion beam. The device further includes a sample transfer system, comprising a sample manipulator including a sample holder for receiving at least one sample. The device additionally includes an in-coupling system for the vacuum-tight connection of the ion beam tube to the measurement chamber, which comprises an ion beam vacuum feedthrough, at least one receiver for a detector, a receiver for receiving the sample observation unit, and a receiver for receiving the sample transfer system. The in-coupling system represents a direct mechanical connection between the components that are the ion lens system, detector and sample observation unit.

Abstract: A method for preparing a lithium ion solid-state accumulator comprising an anode, a cathode, and a solid-state electrolyte includes pressing and sintering pre-calcined electrolyte powder to an electrolyte layer. The pre-calcined electrolyte powder comprises at least one phosphate compound, at least one silicide compound, or at least one phosphorus sulfide. The method further includes applying, on both sides of the electrolyte layer, one electrode each. Prior to the application of the at least one electrode layer on a surface of the sintered electrolyte layer, first, at least one intermediate layer, and, then, on this intermediate layer, the electrode layer is applied. The at least one intermediate layer is a layer of electrolyte and anode material and/or a layer of electrolyte and cathode material.

Abstract: The present invention relates to a composition consisting of or containing peptides selected from the group consisting of or containing RD2, D3, homologs having at least 50% identity and derivatives of RD2 or D3 and also polymers containing or consisting of RD2/D3 homologs having at least 50% identity and derivatives of RD2 and under D3 for use as an analgesic, for use in pain therapy, for use in the treatment of chronic and/or neuropathic pain and/or for inhibiting N-type neuronal calcium channels (NCCs).

Abstract: The invention concerns a method for detecting indicators for determining diseases (disease indicators), in which aggregates of misfolded proteins play a role, and a method for selective quantitation and/or characterization of these disease indicators.

Abstract: According to a method for producing a nanostructured electrode for an electrochemical cell, in which active material is applied to an electrically conductive substrate, the active material is deposited on the electrically conductive substrate by magnetron sputtering in one process step, a ceramic target comprising an electrode material having an additional carbon proportion between 0.1 and 25% by weight is used, the substrate being kept at temperatures between 400° C. and 1200° C. during the deposition, in such a way that a fibrous porous network is formed.

Abstract: Disclosed is a biphasic electrically conductive perovskite-based mixed oxide of the structure ABO3 with A=Ba, and B=Co, comprising additionally 5-45 at %, preferably 15 to 30 at %, particularly preferably 25 at % Co3O4 (at % Co based on the total number of Co atoms in the perovskite ABO3 and 0.5 to 0.3 at %, preferably 1 to 2.5 at %, particularly preferably 2 at % (wherein the at % are referred to the total number of B cations in the perovskite ABO3) Ti as dopant. Preferably, the mixed oxide has the stoichiometric formula BaCo1?xTixO3??:Co3O4 with x=0.005 to 0.03, preferably x=0.01 to 0.025, particularly preferably x=0.02, wherein ? defines the vacancies in the perovskite structure and is in the range of about 0.1 to 0.8, preferably 0.3 to 0.7, particularly preferably about 0.5 to 0.6.

Abstract: An electrolyte includes at least one lithium salt, at least one first organic solvent having a dielectric constant of >90 at 40° C., at least one second organic solvent having a boiling point of <110° C., and at least one phosphite having the formula (I) R1 is selected from an n-propoxy group, an iso-propoxy group, a tert-butoxy group, an n-pentafluoropropoxy group, an n-trifluoropropoxy group, an iso-hexafluoropropoxy group, or a tert-nonafluorobutoxy group. R2, R3, R4, and R5 are each selected, independently of one another, from H, a trifluoromethyl group, or a C2-C6-alkyl group which is substituted with a trifluoromethyl group.

Abstract: A method for producing a hybrid structure, the hybrid structure including at least one structured Majorana material and at least one structured superconductive material arranged thereon includes producing, on a substrate, a first mask for structured application of the Majorana material and a further mask for structured growth of the at least one superconductive material, which are aligned relatively to one another, and applying the at least one structured superconductive material to the structured Majorana material with the aid of the further mask. The structured application of the Majorana material and of the at least one superconductive material takes place without interruption in an inert atmosphere.

Abstract: A method for the determining a position of at least one measurement object equipped with a mobile station having a receiver includes employing at least four reference objects having a base station and a transmitter, wherein a first reference object of the at least four reference objects has a mobile station with a receiver and simultaneously acts as a measurement object. The base station and the mobile station are structurally combined. The reference objects initially have a known position that can change. The transmitters of the base stations transmit signals and the mobile stations receive signals. The method additionally includes emitting, by at least two transmitters of base stations, periodic signals of different frequencies at mutually defined time intervals, wherein these frequencies are closely adjacent.

Abstract: A construction element, particularly adapted and configured for use in a turbo engine, in particular an aircraft engine, wherein a bond coat having a bond structure and thereabove a ceramic coat are disposed on a base. The lateral faces of the bond structure in the cross section are configured so as to be free of undercuts, wherein peak structures and/or trough structures are present, and the peak of the cross section of a peak structure has a mean peak angle (?) of less than or equal to 90°, most particularly less than 45°, and/or the trough structure has a valley angle in the range 90°??<170°.

Abstract: A method for sintering metallic and/or non-oxide components includes completely encapsulating, in a metal halide salt, a green body comprising at least one metallic and/or non-oxide powder, and compressing the encapsulated green body so as to be gastight. The method further includes heating, together with a metal halide salt in the presence of oxygen up to sintering temperatures, the compressed, encapsulated green body. The method additionally includes at least partially dissolving, after cooling, the metal halide salt in a liquid so that the sintered component can be removed.

Abstract: A method for two-dimensional imaging of a positron emitter distribution in objects to be examined, wherein the object to be examined includes a positron emitter, includes positioning the object to be examined in a magnetic field, wherein the positrons leaving the object to be examined follow the course of the magnetic field and strike a positron absorber which is likewise positioned in the magnetic field and which, upon interaction with the positrons, allows localization of the impact points of the positrons on the positron absorber.

Abstract: A dipole antenna assembly includes at least two dipole antennas mechanically, but not electrically, connected to each other. The at least two dipole antennas cross at an intersection point and form dipole antenna arms starting from the intersection point. The dipole antenna arms are arranged in a half-space.

Abstract: An SiPM sensor chip includes pixels consisting of microcells Z, each pixel being associated with an xy position x1, x2, x3, . . . , xN or y1, y2, y3, . . . yM. A plurality of pixels form a block, and the microcells are connected to output channels for a linear coding.

Abstract: An electromagnetic sensing device comprising: a reference microfluidic reservoir to receive a reference substance with magnetic nanoparticles; an analyte microfluidic reservoir to receive an analyte and magnetic nanoparticles; a first excitation magnetic coil to subject the reference microfluidic reservoir to an alternating magnetic field at a first frequency; a second excitation magnetic coil to subject the analyte microfluidic reservoir to an alternating magnetic field at the first frequency; a third excitation magnetic coil to subject the reference microfluidic reservoir to an alternating magnetic field at a second frequency distinct from the first frequency; a fourth excitation magnetic coil to subject the analyte microfluidic reservoir to an alternating magnetic field at the second frequency; a first detection magnetic coil to detect a response magnetic field of the magnetic nanoparticles in the reference microfluidic reservoir; a second detection magnetic coil to detect a response magnetic field of the