Abstract: A device for autologous blood transfusion includes a centrifuge unit with an autotransfusion set rotatably mounted thereto. The autotransfusion set includes a separation unit for concentrating a cell fraction by centrifugation and a tubing system for providing a connection to a blood supply. The tubing system includes a blood supply line leading to the separation unit for supplying blood to be processed and a return line leading away from the separation unit. A filter is integrated into the autotransfusion set in order to eliminate leukocytes and/or tumor cells, thereby yielding greater safety in autotransfusion.
Abstract: A multi-lumen tube arrangement for use in a centrifuge free of a sliding seal, the tube arrangement having at least two individual tubes which are rotated around one another around their longitudinal and/or their parallel axes. The rotation of the tubes takes place in this connection in opposite directions starting from a support position disposed approximately centrally in order to compensate the torques applied to the tube arrangement. A method for manufacturing such a tube arrangement is also decribed.
Abstract: A centrifuge having a rotating frame, which is rotatably mounted on a stationary frame, and a separation unit mounted on the rotating frame, rotating about a central axis of rotation in the same direction of rotation as the rotating frame but at twice the rotational speed. A line for supplying and/or removing a fluid is connected to the separation unit and is guided in a loop about the separation unit to a stationary tie-in point. To support the line, at least one guide element having a bearing surface for the line is provided. The bearing surface of the guide element is formed by a rotating planar curve, where the radius of the respective circle of curvature contacts the curve at a point and increases with increasing distance between the contact point and the central axis of rotation. With this contour, abrasion over the entire contact surface is largely uniform, which thereby lengthens the lifetime.
Abstract: A process for manufacturing an adsorbent for reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma in which a carrier material, which is preferably a copolymer derived from (meth)acrylates and or (meth)acrylic acid amides, is activated by amination, and subsequently undergoes thermal treatment at a temperature of over 100° C. An adsorber for the purpose of reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma may be produced from the adsorbent.
Type:
Grant
Filed:
March 9, 2001
Date of Patent:
March 30, 2004
Assignee:
Fresenius HemoCare GmbH
Inventors:
Hans-Peter Leinenbach, Heike Mitschulat, Wolfgang Metzger, Veit Otto, Martin Hepper
Abstract: An adsorbent for reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma comprises a matrix and synthetic lateral chains that are covalently bonded to the matrix. The lateral synthetic chains are comprised of at least two amino groups in which the N2 atoms are at least 2.6 Å apart within at least one lateral synthetic chain. The matrix exhibits porous, unaggregated, spherical particles in a range of particle sizes from 50 to 250 &mgr;m, which possess an exclusionary threshold of at least 107 Daltons, and they exhibit no peptides or aromatic groups of any kind. The at least two amino groups are preferably separated from one another by 4 to 6 carbon atoms. An adsorber for the purpose of reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma may be produced from the adsorbent.
Type:
Grant
Filed:
March 9, 2001
Date of Patent:
October 28, 2003
Assignee:
Fresenius HemoCare GmbH
Inventors:
Hans-Peter Leinenbach, Veit Otto, Martin Hepper
Abstract: A method for determining the particle concentration of a continuous medium in a receptacle, in which, a light beam from a light source is first directed through a particle-loaded, continuous medium, to the light-sensitive surface of a position-sensitive sensor, the light beam being so directed at the light-sensitive surface that the light scattered by the particles assuming, on the average, a different position than the unscattered light. The deviation of the midpoint of the scattered light on the light-sensitive surface from the midpoint of the unscattered light is subsequently determined, and this deviation is correlated to a specific particle concentration.
Abstract: A magnetic gear having first and second carrier each having a plurality of magnetic poles arranged in a circle and separated by a distance, with the north and south poles arranged in alternation. Flux-carrying connecting pieces are provided on a third carrier to magnetically couple the first and second carriers. A centrifuge for centrifuging biological fluids, especially blood, having such a magnetic gear includes a first carrier in a stationary mount on a frame, while the third carrier is a rotating frame in a rotating mount on the frame. The second carrier is a separation unit mounted on the rotating frame. The centrifuge using the magnetic gear allows maintenance-free operation at a high rpm and with low noise, requiring a relatively low driving power.