Abstract: A method is provided of monitoring the leak tightness of a plurality of pneumatically or hydraulically actuated actuators of a machine, in particular a plurality of valve actuators of a medical treatment machine, in which pressure is exerted on the actuators in different combinations during operation of the machine. A common pressure drop occurring during a stationary operating phase at the actuators on which pressure is exerted in the respective combination is measured for a plurality of different combinations of actuators on which pressure is exerted. A respective leak tightness value is determined for individual actuators and/or groups of actuators, with the pressure drop measured for those combinations and in which the respective actuator and/or the respective group of actuators on which pressure is exerted being accounted for in the leak tightness value. A machine, in particular a medical treatment machine, is configured to effect the valve actuator monitoring.

Abstract: The invention relates to an insert and a vial for the infusion of a liquid. The vial comprises a hollow body, a grasp portion and a head. The head comprises a delivery opening defining an axis X; a septum for closing the opening; and at least one circumferential push surface next to the head and firmly connected to the grasp portion. The insert is suitable to deliver the liquid and to receive the vial along axis X. The insert comprises a main body with lower ducts, an inner part and a piercing spike. The inner part defines a seat for the vial head, and comprises one slit for engaging the circumferential push surface. The spike is suitable to pierce the vial septum and defines upper ducts. The inner part is able to rotate inside the main body between a fluidly open configuration and a fluidly closed configuration.