Abstract: The present invention relates to specific T-cell receptor a-chains, T-cell receptor ?-chains and T-cell receptors comprising said T-cell receptor a-chain and/or ?-chain. In particular, the invention relates to T-cell receptors and/or chains binding to the influenza matrix peptide GILGFVFTL (GL9 peptide) presented by Human Leukocyte antigen A2 (HLA-A2) molecules. The present invention further relates to soluble TCR constructs, chimeric TCRs, nucleic acids, expression constructs and cells comprising said TCR a-chain and/or ?-chain or the respective TCR. The present invention further relates to the use of the TCR a-chain and/or ?-chain or the respective TCR or the soluble TCR constructs or chimeric TCRs as a medicament, preferably in the detection, prevention and/or treatment of influenza. The present invention further relates to methods of detecting, preventing and/or treating influenza.

Abstract: A method for detecting a degree of hydrogenation of a liquid comprises one or more liquid hydrogen carriers, which can be hydrogenated, comprising: detecting a material property of the liquid and determining the degree of hydrogenation of the liquid on the basis of the detected material property of the liquid.

Abstract: The invention relates to a zeolitic material comprising zeolitic monocrystals, each of which has a pore system encompassing at least one micropore system and at least one macropore system, and to a method for producing a zeolitic material of said type. In said method, porous oxide particles are converted into the zeolitic material in the presence of an organic template and steam.

Abstract: The invention relates to methods for the intra-amniotic administration of EDA agonists, in particular EDI200. Use of the methods described allow for the design of targeted therapeutic dosing and administration regimens in order to correct or alter abnormal phenotypes associated with ectodermal dysplasias, in particular, XLHED.

Abstract: A local wave field synthesis apparatus, which includes a determination module for determining desired sound pressures and desired particle velocity vectors at a plurality of control points, a computation module for computing sound pressures and particle velocity vectors at the plurality of control points based on a set of filter parameters, an optimization module for computing an optimum set of filter parameters by jointly optimizing computed sound pressures towards the desired sound pressures and computed particle velocity vectors towards the desired particle velocity vectors, and a generator module for generating the drive signals based on the optimum set of filter parameters, wherein the plurality of control points are located on one or more contours around the one or more audio zones.

Abstract: The invention relates to a method for the frequency error correction of an oscillator of a sensor node in a sensor network, comprising the following steps: receiving a transmission signal of a transmitter, the signal being modulated by orthogonal frequency division multiplexing (OFDM); determining the frequency deviation of the oscillator using the received transmission signal; determining a correction signal for correcting the frequency deviation of the oscillator and correcting the frequency of the oscillator by means of the correction signal.

Abstract: A method for calibrating a time difference of arrival-based local positioning system for k?D localization, k=2 or 3, includes collecting N sets of time difference of arrival measurements related to a mobile node, N?2, each nth set of measurements being performed by Bn beacon nodes among B beacon nodes of the positioning system while the mobile node is located is a nth position within a region covered by the positioning system, Bn?k+2, and determining optimal beacon positions that minimize an objective function depending on N residual error vectors, the calculation of each nth position of the mobile node using beacon positions and the nth set of measurements, the calculation allowing the calculation of the nth residual error vector.

Abstract: A method for calculating a position of an object of interest in an environment. The method includes: predicting a position and an orientation of the object of interest in the environment; selecting a subset of base stations among a set of base stations located within the environment, by using the predicted position and orientation, and a radiation pattern of a system including the object of interest and a mobile transponder attached to the object of interest; and calculating an actual position of the object of interest, using time of arrival or time difference of arrival measurements between the base stations of the subset and the mobile transponder.

Abstract: An apparatus for generating at least one audio output signal based on an audio data stream having audio data relating to one or more sound sources is provided. The apparatus has a receiver for receiving the audio data stream having the audio data. The audio data has one or more pressure values for each one of the sound sources. Furthermore, the audio data has one or more position values indicating a position of one of the sound sources for each one of the sound sources. Moreover, the apparatus has a synthesis module for generating the at least one audio output signal based on at least one of the one or more pressure values of the audio data of the audio data stream and based on at least one of the one or more position values of the audio data of the audio data stream.

Abstract: An RFID reader includes a transmitter, a receiver, and an evaluator. The receiver receives signals from RFID tags within a given number of slots of a time frame with a given frame size and provides a number of successful slots and a number of collided slots. The evaluator sets a modified frame size based on an estimated number of RFID tags which is determined based on the frame size, the number of successful slots, and the number of collided slots. The invention also refers to a corresponding method.

Abstract: A measurement method is for determining core losses, which serve to produce magnetic circuits for electrical machines. In order to allow an accurate measurement that is as quick as possible, it is proposed that a magnetic coupling is produced between a measuring coil connected in a capacitor and a core to be measured, and the measuring coil is then acted upon by an alternating frequency in order to measure the resonant frequency of the resulting resonant circuit and/or the quality of the resulting resonant circuit as a measure of the core loss.

Abstract: The invention relates to dendritic cells, the NF?B signaling pathway of which has been manipulated by RNA transfection, to the manufacture thereof and to use thereof.

Abstract: The invention relates to an electron beam splitter (1) comprising a multi-pole electrode arrangement with a high-frequency alternating current voltage (5), which extends along a specified path (6) from an inlet side (9) to an outlet side (10), wherein the electrode arrangement (5) generates on the inlet side (9) with a first number of electrodes (7) impacted by the voltage a first oscillating electric field (61), which forms on a transversal plane a single local confinement minimum (62) in a time-averaged manner, and wherein the electrode arrangement (5) generates at least on the outlet side (10) with a second number of voltage-impacted electrodes (7) a second oscillating electric field (65), which forms at least two local confinement minimums (66, 67) in a time averaged manner.

Abstract: Images of an object, such as OCT scans of a human eye, can include distortions and data gaps due to relative motion of the object and the image acquisition device. Methods and systems for correction of such distortions and data gaps are described herein. Motion-corrected data is arrived at by applying three-dimensional transforms to input three-dimensional data sets that represent at least partially overlapping regions of the imaged object. The three dimensional transforms are computed based on an objective function that accounts for similarity between the transformed three-dimensional data sets and the estimated motion of the object relative to an imaging instrument. Methods and systems described herein advantageously eliminate the need for postulated assumptions and reliance on landmarks and are capable of filling data gaps, thereby producing high quality, undistorted images of objects subject to movement during imaging.

Abstract: A method and device for diagnosing an electrical condition of a spatially extended hardware component in a spatially resolved manner via interference between pulses fed into the component by a signal generator. The method includes: feeding at least two pulses into the component offset by a pulse interval; detecting the interfered pulses and echoes via an analysis unit; varying the pulse interval for the spatially resolved scanning of the hardware component along its length; repeating the steps until the component has been scanned at least in some sections; and analyzing the detected interfered pulses in the analysis unit. The device includes at least one signal generator connected to the component and to an analysis unit to generate the pulses, wherein local energy losses are mathematically determined over the length of the component on the basis of a plurality of interference voltage waveforms and voltage waveforms induced by the pulses.

Abstract: The invention relates to dendritic cells, the NF?B signaling pathway of which has been manipulated by RNA transfection, to the manufacture thereof and to use thereof.

Abstract: Described are methods and means for metabolic engineering and improved product formation by a filamentous micro-organism or a low G+C gram-positive bacterium. Disclosed is that DasR and DasR binding sites play an important and universal role in the control of gene expression in micro-organisms. Based on this finding, provided are multiple useful applications, such as a method for regulating the expression of a gene of interest, a method for controlling metabolism, a method for decreasing undesired expression and many more. Moreover, provided are means that can be used to establish said methods: for example a micro-organism in which the DasR binding site in operable linkage with a particular gene has been modified to obtain increased or decreased expression of a protein (being a desired or undesired protein) encoded by said gene.

Abstract: An apparatus for providing one or more adjusted parameters for a provision of an upmix signal representation on the basis of a downmix signal representation and an object-related parametric information includes a parameter adjuster. The parameter adjuster is configured to receive one or more input parameters and to provide, on the basis thereof, one or more adjusted parameters. The parameter adjuster is configured to provide the one or more adjusted parameters in dependence on the one or more input parameters and the object-related parametric information, such that a distortion of the upmix signal representation caused by the use of non-optimal parameters is reduced at least for input parameters deviating from optimal parameters by more than a predetermined deviation.

Abstract: In a device and a corresponding method for joining a plurality of individual digital images to form a total image, a plurality of features is determined in a first individual image by means of a selection unit using a feature-based algorithm and then tracked in a second individual image by means of a tracking unit. A transformation matrix, with which the individual images are joined in an output unit to form the total image, is calculated from the determined feature correspondences in a transformation unit. The individual images can be joined in real time and with a high degree of accuracy by means of the feature-based algorithm in combination with a robust algorithm to calculate the transformation matrix.

Abstract: A detection device for detecting a blood count parameter of a blood component in a blood vessel comprising a transmitter, a receiver, a loss detector, and a processor. The transmitter injects a first transmit signal into the blood vessel at a first frequency and a second transmit signal into the blood vessel at a second frequency. The receiver receives a first receive signal at the first frequency and a second receive signal at the second frequency. The loss detector determines a first loss value on the basis of the first transmit signal and the first receive signal, and determines a second loss value on the basis of the second transmit signal and the second receive signal. The processor determines a relaxation time constant of the blood component in accordance with the frequency having the greater loss value, and determines the blood count parameter in accordance with the determined relaxation time constant.