Patents Assigned to Functional Neuromodulation Inc.
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Publication number: 20230218901Abstract: Methods and apparatus for improving cognitive function within a human. The invention utilizes an implanted device, such as an implantable signal generator or an implantable pump, to affect tissue elements within a Papez circuit of the human brain as well as tissue upstream or downstream from the Papez circuit. The implanted device delivers treatment therapy to thereby improve cognitive function by the human. A sensor may be used to detect various symptoms of the cognitive disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate delivery of the stimulation and/or drug therapy.Type: ApplicationFiled: November 17, 2022Publication date: July 13, 2023Applicant: Functional Neuromodulation, Inc.Inventor: Andres M. Lozano
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Publication number: 20230173257Abstract: Methods and apparatus for inducing neurogenesis within a human. The invention utilizes an implantable signal generator to deliver high frequency stimulation to deep brain tissue elements. The implanted device delivers treatment therapy to the brain to thereby induce neurogenesis by the human. A sensor may be used to detect various symptoms of nervous system discovery. A microprocessor algorithm may then analyze the output from the sensor to regulate the stimulation and/or drug therapy delivered to the brain.Type: ApplicationFiled: July 12, 2022Publication date: June 8, 2023Applicant: Functional Neuromodulation, Inc.Inventors: Andres M. Lozano, Hiroki Toda
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Publication number: 20230096192Abstract: Systems and methods for treating a cognitive disease or disorder are provided. A treatment method comprises: selecting a target volume of brain tissue to be stimulated; identifying at least one avoidance volume of brain tissue; selecting a first stimulation lead comprising at least one stimulation element; identifying at least one proposed trajectory for placement of the first stimulation lead based on the target volume and the at least one avoidance volume; placing the first stimulation lead along a placement trajectory selected from the at least one proposed trajectory; attaching the first stimulation lead to a stimulator; and stimulating the target volume with the first stimulation lead at least one stimulation element to treat at least one of a cognitive disease or a cognitive disorder. Systems include a stimulator with one or more stimulation leads and an image analyzer for identifying a proposed trajectory for placing the stimulation leads.Type: ApplicationFiled: November 11, 2022Publication date: March 30, 2023Applicant: Functional Neuromodulation, Inc.Inventors: Donald E. Reymers, Mark Rise, Daniel J. O'Connell, R. Maxwell Flaherty, J. Christopher Flaherty
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Publication number: 20220008727Abstract: A system for treating a patient comprises a stimulator for stimulating brain tissue, a controller for setting stimulation parameters and a diagnostic tool for measuring patient parameters and producing diagnostic data. The stimulation parameters comprise test stimulation parameters and treatment stimulation parameters. The stimulator delivers test stimulation energy to the brain tissue based on at least one test stimulation parameter and delivers treatment stimulation energy to the brain tissue based on at least one treatment stimulation parameter. One or more treatment stimulator parameters are determined based on the diagnostic data produced by the diagnostic tool The system is constructed and arranged to treat a neurological disease or a neurological disorder. Methods of treating a neurological disease or neurological disorder are also provided.Type: ApplicationFiled: February 26, 2021Publication date: January 13, 2022Applicant: Functional Neuromodulation, Inc.Inventors: Dan O'Connell, Todd Langevin, Donald E. Reymers, J. Christopher Flaherty
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Publication number: 20210275815Abstract: Methods and apparatus for improving cognitive function within a human. The invention utilizes an implanted device, such as an implantable signal generator or an implantable pump, to affect tissue elements within a Papez circuit of the human brain as well as tissue upstream or downstream from the Papez circuit. The implanted device delivers treatment therapy to thereby improve cognitive function by the human. A sensor may be used to detect various symptoms of the cognitive disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate delivery of the stimulation and/or drug therapy.Type: ApplicationFiled: October 14, 2020Publication date: September 9, 2021Applicant: Functional Neuromodulation, Inc.Inventor: Andres M. Lozano
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Publication number: 20200398055Abstract: A system for treating a patient comprises a stimulator for stimulating brain tissue, a controller for setting stimulation parameters and a diagnostic tool for measuring patient parameters and producing diagnostic data. The stimulation parameters comprise test stimulation parameters and treatment stimulation parameters. The stimulator delivers test stimulation energy to the brain tissue based on at least one test stimulation parameter and delivers treatment stimulation energy to the brain tissue based on at least one treatment stimulation parameter. One or more treatment stimulator parameters are determined based on the diagnostic data produced by the diagnostic tool The system is constructed and arranged to treat a neurological disease or a neurological disorder. Methods of treating a neurological disease or neurological disorder are also provided.Type: ApplicationFiled: January 24, 2020Publication date: December 24, 2020Applicant: Functional Neuromodulation, Inc.Inventors: J. Christopher Flaherty, Daniel J. O'Connell, Todd Langevin, R. Maxwell Flaherty
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Publication number: 20200246611Abstract: Methods and apparatus for inducing neurogenesis within a human. The invention utilizes an implantable signal generator to deliver high frequency stimulation to deep brain tissue elements. The implanted device delivers treatment therapy to the brain to thereby induce neurogenesis by the human. A sensor may be used to detect various symptoms of nervous system discovery. A microprocessor algorithm may then analyze the output from the sensor to regulate the stimulation and/or drug therapy delivered to the brain.Type: ApplicationFiled: August 19, 2019Publication date: August 6, 2020Applicant: Functional Neuromodulation Inc.Inventors: Andres M. Lozano, Hiroki Toda
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Patent number: 10576283Abstract: A system for treating a patient comprises a stimulator for stimulating brain tissue, a controller for setting stimulation parameters and a diagnostic tool for measuring patient parameters and producing diagnostic data. The stimulation parameters comprise test stimulation parameters and treatment stimulation parameters. The stimulator delivers test stimulation energy to the brain tissue based on at least one test stimulation parameter and delivers treatment stimulation energy to the brain tissue based on at least one treatment stimulation parameter. One or more treatment stimulator parameters are determined based on the diagnostic data produced by the diagnostic tool The system is constructed and arranged to treat a neurological disease or a neurological disorder. Methods of treating a neurological disease or neurological disorder are also provided.Type: GrantFiled: February 13, 2017Date of Patent: March 3, 2020Assignee: Functional Neuromodulation, Inc.Inventors: J. Christopher Flaherty, Daniel J. O'Connell, Todd Langevin, R. Maxwell Flaherty
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Patent number: 10384053Abstract: Methods and apparatus for inducing neurogenesis within a human. The invention utilizes an implantable signal generator to deliver high frequency stimulation to deep brain tissue elements. The implanted device delivers treatment therapy to the brain to thereby induce neurogenesis by the human. A sensor may be used to detect various symptoms of nervous system discovery. A microprocessor algorithm may then analyze the output from the sensor to regulate the stimulation and/or drug therapy delivered to the brain.Type: GrantFiled: November 15, 2013Date of Patent: August 20, 2019Assignee: Functional Neuromodulation Inc.Inventors: Andres M. Lozano, Hiroki Toda
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Publication number: 20190126044Abstract: Methods and apparatus for improving cognitive function within a human. The invention utilizes an implanted device, such as an implantable signal generator or an implantable pump, to affect tissue elements within a Papez circuit of the human brain as well as tissue upstream or downstream from the Papez circuit. The implanted device delivers treatment therapy to thereby improve cognitive function by the human. A sensor may be used to detect various symptoms of the cognitive disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate delivery of the stimulation and/or drug therapy.Type: ApplicationFiled: April 30, 2018Publication date: May 2, 2019Applicant: Functional Neuromodulation, Inc.Inventor: Andres M. Lozano
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Publication number: 20180243565Abstract: A system for treating a patient comprises a stimulator for stimulating brain tissue, a controller for setting stimulation parameters and a diagnostic tool for measuring patient parameters and producing diagnostic data. The stimulation parameters comprise test stimulation parameters and treatment stimulation parameters. The stimulator delivers test stimulation energy to the brain tissue based on at least one test stimulation parameter and delivers treatment stimulation energy to the brain tissue based on at least one treatment stimulation parameter. One or more treatment stimulator parameters are determined based on the diagnostic data produced by the diagnostic tool The system is constructed and arranged to treat a neurological disease or a neurological disorder. Methods of treating a neurological disease or neurological disorder are also provided.Type: ApplicationFiled: September 25, 2017Publication date: August 30, 2018Applicant: Functional Neuromodulation, Inc.Inventors: Dan O'Connell, Todd Langevin, Donald E. Reymers, J. Christopher Flaherty
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Publication number: 20180071519Abstract: Methods and apparatus for inducing neurogenesis within a human. The invention utilizes an implantable signal generator to deliver high frequency stimulation to deep brain tissue elements. The implanted device delivers treatment therapy to the brain to thereby induce neurogenesis by the human. A sensor may be used to detect various symptoms of nervous system discovery. A microprocessor algorithm may then analyze the output from the sensor to regulate the stimulation and/or drug therapy delivered to the brain.Type: ApplicationFiled: November 15, 2013Publication date: March 15, 2018Applicant: Functional Neuromodulation Inc.Inventors: Andres M. Lozano, Hiroki Toda
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Publication number: 20170368354Abstract: Methods and apparatus for improving cognitive function within a human. The invention utilizes an implanted device, such as an implantable signal generator or an implantable pump, to affect tissue elements within a Papez circuit of the human brain as well as tissue upstream or downstream from the Papez circuit. The implanted device delivers treatment therapy to thereby improve cognitive function by the human. A sensor may be used to detect various symptoms of the cognitive disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate delivery of the stimulation and/or drug therapy.Type: ApplicationFiled: January 6, 2017Publication date: December 28, 2017Applicant: Functional Neuromodulation Inc.Inventor: Andres M. Lozano
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Patent number: 9782590Abstract: A system for treating a patient comprises a stimulator for stimulating brain tissue, a controller for setting stimulation parameters and a diagnostic tool for measuring patient parameters and producing diagnostic data. The stimulation parameters comprise test stimulation parameters and treatment stimulation parameters. The stimulator delivers test stimulation energy to the brain tissue based on at least one test stimulation parameter and delivers treatment stimulation energy to the brain tissue based on at least one treatment stimulation parameter. One or more treatment stimulator parameters are determined based on the diagnostic data produced by the diagnostic tool The system is constructed and arranged to treat a neurological disease or a neurological disorder. Methods of treating a neurological disease or neurological disorder are also provided.Type: GrantFiled: October 16, 2014Date of Patent: October 10, 2017Assignee: Functional Neuromodulation, Inc.Inventors: Dan O'Connell, Todd Langevin, Donald E. Reymers, J. Christopher Flaherty
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Patent number: 9669216Abstract: Disclosed are methods for regulating neurotrophin levels within a human body. The invention utilizes an implantable signal generator to deliver stimulation to neural tissue elements. Alternatively, an implantable pump may be utilized to delivery one or more drugs. The implanted device delivers treatment therapy to the neural tissue to thereby alter the level of neurotrophic factors such as BDNF expressed by the influenced neural tissue. A sensor may be used to detect various symptoms of a nervous system disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate the treatment therapy delivered to the body. The invention describes a novel method to regulate the intrinsic levels of neurotrophins and may be used to treat patients with neurological and cognitive disorders.Type: GrantFiled: December 21, 2015Date of Patent: June 6, 2017Assignee: Functional Neuromodulation Inc.Inventor: Andres M. Lozano
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Publication number: 20170151436Abstract: A system for treating a patient comprises a stimulator for stimulating brain tissue, a controller for setting stimulation parameters and a diagnostic tool for measuring patient parameters and producing diagnostic data. The stimulation parameters comprise test stimulation parameters and treatment stimulation parameters. The stimulator delivers test stimulation energy to the brain tissue based on at least one test stimulation parameter and delivers treatment stimulation energy to the brain tissue based on at least one treatment stimulation parameter. One or more treatment stimulator parameters are determined based on the diagnostic data produced by the diagnostic tool The system is constructed and arranged to treat a neurological disease or a neurological disorder. Methods of treating a neurological disease or neurological disorder are also provided.Type: ApplicationFiled: February 13, 2017Publication date: June 1, 2017Applicant: Functional Neuromodulation Inc.Inventors: J. Christopher Flaherty, Dan O'Connell, Todd Langevin, R. Maxwell Flaherty
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Publication number: 20160030666Abstract: The present invention involves a method and a system for using electrical stimulation and/or chemical stimulation to treat a cognitive impairment and/or disorder. More particularly, the method comprises surgically implanting an electrode and/or catheter that is in communication with a predetermined site which is coupled to a pulse generating source and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the cognitive disorder and/or enhancing the cognitive ability.Type: ApplicationFiled: December 30, 2014Publication date: February 4, 2016Applicant: Functional Neuromodulation, Inc.Inventors: Andres M. Lozano, Helen S. Mayberg
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Patent number: 9227066Abstract: Disclosed are methods for regulating neurotrophin levels within a human body. The invention utilizes an implantable signal generator to deliver stimulation to neural tissue elements. Alternatively, an implantable pump may be utilized to delivery one or more drugs. The implanted device delivers treatment therapy to the neural tissue to thereby alter the level of neurotrophic factors such as BDNF expressed by the influenced neural tissue. A sensor may be used to detect various symptoms of a nervous system disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate the treatment therapy delivered to the body. The invention describes a novel method to regulate the intrinsic levels of neurotrophins and may be used to treat patients with neurological and cognitive disorders.Type: GrantFiled: October 7, 2014Date of Patent: January 5, 2016Assignee: FUNCTIONAL NEUROMODULATION INC.Inventor: Andres M. Lozano
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Publication number: 20150142089Abstract: Methods and apparatus for inducing neurogenesis within a human. The invention utilizes an implantable signal generator to deliver high frequency stimulation to deep brain tissue elements. The implanted device delivers treatment therapy to the brain to thereby induce neurogenesis by the human. A sensor may be used to detect various symptoms of nervous system discovery. A microprocessor algorithm may then analyze the output from the sensor to regulate the stimulation and/or drug therapy delivered to the brain.Type: ApplicationFiled: November 15, 2013Publication date: May 21, 2015Applicant: Functional Neuromodulation Inc.Inventors: Andres M. Lozano, Hiroki Toda
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Patent number: 8868191Abstract: Disclosed are methods for regulating neurotrophin levels within a human body. The invention utilizes an implantable signal generator to deliver stimulation to neural tissue elements. Alternatively, an implantable pump may be utilized to delivery one or more drugs. The implanted device delivers treatment therapy to the neural tissue to thereby alter the level of neurotrophic factors such as BDNF expressed by the influenced neural tissue. A sensor may be used to detect various symptoms of a nervous system disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate the treatment therapy delivered to the body. The invention describes a novel method to regulate the intrinsic levels of neurotrophins and may be used to treat patients with neurological and cognitive disorders.Type: GrantFiled: January 22, 2013Date of Patent: October 21, 2014Assignee: Functional Neuromodulation, Inc.Inventor: Andres M. Lozano