Abstract: A method of inhibiting postoperative adhesion severity of mammalian tissues. The method includes the application on an operated tissue surface of an effective therapeutic amount of a pharmaceutical composition containing a pharmaceutically acceptable amount of growth factors and sterilized carboxymethylchitosan. A method of inhibiting postoperative adhesion severity that includes the step of applying a composition comprising a growth factor, where the growth factor is used as a modulating factor on mesothelial cell proliferation is also provided.
Type:
Grant
Filed:
March 18, 2013
Date of Patent:
January 5, 2016
Assignees:
JACKSON BRANDAO LOPES, LUIS ALBERTO OLIVERIA DALLAN, FUNDACAO SAO FRANCISCO XAVIER
Inventors:
Jackson Brandão Lopes, Luis Alberto Oliveira Dallan
Abstract: The present invention refers to the use of growth factors, which are effective on mesothelial cell proliferation, used in a sterilized carboxymethylchitosan pharmaceutical composition employed to reduce postoperative adhesions severity. The present invention also provides a method to inhibit postoperative adhesions severity.
Type:
Grant
Filed:
March 19, 2009
Date of Patent:
November 18, 2014
Assignees:
Fundacao Sao Francisco Xavier
Inventors:
Jackson Brandão Lopes, Luis Alberto Oliveira Dallan
Abstract: A method of inhibiting postoperative adhesion severity of mammalian tissues. The method includes the application on an operated tissue surface of an effective therapeutic amount of a pharmaceutical composition containing a pharmaceutically acceptable amount of growth factors and sterilized carboxymethylchitosan. A method of inhibiting postoperative adhesion severity that includes the step of applying a composition comprising a growth factor, where the growth factor is used as a modulating factor on mesothelial cell proliferation is also provided.
Type:
Application
Filed:
March 18, 2013
Publication date:
August 22, 2013
Applicant:
FUNDAÇÃO SÃO FRANCISCO XAVIER
Inventors:
Fundação São Francisco Xavier, Jackson Brandão Lopes, Luis Alberto Oliveira Dallan
Abstract: The present invention refers to the use of growth factors, which are effective on mesothelial cell proliferation, used in a sterilized carboxymethylchitosan pharmaceutical composition employed to reduce postoperative adhesions severity. The present invention also provides a method to inhibit postoperative adhesions severity.
Type:
Application
Filed:
March 19, 2009
Publication date:
July 7, 2011
Applicant:
FUNDACAO SAO FRANCISCO XAVIER
Inventors:
Jackson Brandão Lopes, Luis Alberto Oliveira Dallan