Abstract: The present invention relates to granulysin, method of obtaining same, and uses, specifically to the granulysin polypeptide for the use thereof as a medicinal product via the systemic route and to a chimeric molecule comprising a recombinant antibody targeting a tumor antigen and the granulysin polypeptide.
Type:
Grant
Filed:
July 24, 2019
Date of Patent:
January 2, 2024
Assignees:
UNIVERSIDAD DE ZARAGOZA, FUNDACIÓN AGENCIA ARAGONESA PARA LA INVESTIGACIÓN Y EL DESARROLLO (ARAID), FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA
Inventors:
Luis Alberto Anel Bernal, Raquel Ibañez Perez, Patricia Guerrero Ochoa, Luis Martinez Lostao, Blanca Conde Guerri, Ramón Hurtado Guerrero, Ana Laura Sanz Alcober, Rocio Navarro Ortiz
Abstract: The present invention discloses a biosensor for visual detection of an analyte, based on the light to heat conversion properties of metal nanoparticles: the analyte is visually detected by the color change in the support areas (where the analyte is present), produced as a result of the heat generated by the metal nanoparticles where they are irradiated with an external light source. Use of said biosensor in a method for the detection of analytes is also claimed.
Type:
Grant
Filed:
July 26, 2013
Date of Patent:
February 5, 2019
Assignees:
UNIVERSIDAD DE ZARAGOZA, FUNDACIÓN AGENCIA ARAGONESA PARA LA INVESTIGACIÓN Y EL DESARROLLO, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS
Inventors:
Pablo Del Pino González De La Higuera, Beatriz Pelaz Garcia, Ester Polo Tobajas, Valeria Grazú Bonavía, Jesús Martínez De La Fuente, Victor Parro Garcia